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Enxertos e substitutos ósseos em cirurgia ortopédica reconstrutiva nos animais ...

We present here an overview of the scientific literature concerning the clinical application of autografts and allografts of the skeletal tissues and of the natural and synthetic bone graft substitutes available in small animal orthopedic surgery for resolution of congenital, traumatic and tumoral etiology situations or for reconstructive artroplastic surgeries. This article focuses the terminology, definitions...

Canine adipose stem cells : the influence of the anatomy and passaging on the s...

Periodontal disease (PD) is an inflammatory pathology highly prevalent both in humans and in dogs, which is characterized by destruction of the periodontal ligament, cementum and alveolar bone. The development of new therapies, such as Tissue Engineering strategies, is mandatory due to the inefficacy of conventional therapies currently used. Dog is a very relevant animal model to study several human diseases, s...

Synergistic effect of scaffold composition and dynamic culturing environment in...

Bone extracellular matrix (ECM) is composed of mineralized collagen fibrils which support biological apatite nucleation that participates in bone outstanding properties. Understanding and mimicking bone morphological and physiological parameters at a biological scale is a major challenge in tissue engineering scaffolding. Using emergent (nano)technologies scaffold designing may be critically improved, enabling ...

Serum total and bone alkaline phosphatase and tartrate-resistant acid phosphata...

Tissue engineered constructs based on SPCL scaffolds cultured with goat marrow ...

This study aims to assess the in vivo performance of cell–scaffold constructs composed of goat marrow stromal cells (GBMCs) and SPCL (a blend of starch with polycaprolactone) fibre mesh scaffolds at different stages of development, using an autologous model. GBMCs from iliac crests were seeded onto SPCL scaffolds and in vitro cultured for 1 and 7 days in osteogenic medium. After 1 and 7 days, the constructs wer...

Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog

Values of serum tartrate-resistant acid phosphatase (TRAP)activity were obtained in adult dogs and its biological variability was assessed. Nine healthy skeletally mature Portuguese Podengo dogs were used for the determination of TRAP, total and bone alkaline phosphatase serum activities, and also to styudy their relashionship with serum minerals, namely calcium (Ca) phosphorous (P),and magnesium (Mg).The serum...

Tissue engineered constructs based on SPCL scaffolds cultured with goat marrow ...

This study aims to assess the in vivo performance of cell–scaffold constructs composed of goat marrow stromal cells (GBMCs) and SPCL (a blend of starch with polycaprolactone) fibre mesh scaffolds at different stages of development, using an autologous model. GBMCs from iliac crests were seeded onto SPCL scaffolds and in vitro cultured for 1 and 7 days in osteogenic medium. After 1 and 7 days, the constructs wer...

In vitro and in vivo biocompatibility evaluation of k-carrageenan hydrogels aim...

Introduction The development of biomaterials for biomedical applications always requires extensive biological testing to demonstrate the safety of both the material and its degradation components. K-carrageenan is a naturally occurring polysaccharide which forms a hydrogel with potassium ions and the temperature-induced gelation enables its application as an in vitro cell-carrier or as an in vivo injectable sys...

Haematological and biochemical parameters in Churra-da-Terra-Quente ewes from t...

Haematological and biochemical parameters in Churra-da-Terra-Quente ewes from t...

Hematological and biochemical parameters, including plasma electrolytes and thyroid hormones, were determined in 73 clinically healthy Churra-da-Terra-Quente ewes, a typical breed from the northeast of Portugal. The hemogram values were: erythrocytes 9.8±1.51012/L; haemoglobin 118.1±19.1g/L; haematocrit 40.8±5.9%; leukocytes 5.7±1.8109/L; and platelets 544.3±177.2109/L. The thrombin time was 17.3±1.7 seconds...