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Design and characterization of a biodegradable double-layer scaffold aimed at p...
Requicha, J. F.; Viegas, C. A. A.; Hede, Shantesh; Leonor, I. B.; Reis, R. L.; Gomes, Manuela E.The inefficacy of the currently used therapies in achieving the regeneration ad integrum of the periodontium stimulates the search for alternative approaches, such as tissue-engineering strategies. Therefore, the core objective of this study was to develop a biodegradable double-layer scaffold for periodontal tissue engineering. The design philosophy was based on a double-layered construct obtained from a blend...
Biological evaluation of intervertebral disc cells in different formulations of...
Khang, G.; Lee, S. K.; Kim, H. N.; Silva-Correia, J.; Gomes, Manuela E.; Viegas, C. A. A.; Dias, Isabel R.; Oliveira, Joaquim M.; Reis, R. L.Gellan gum (GG)-based hydrogels are advantageous in tissue engineering not only due to their ability to retain large quantities of water and provide a similar environment to that of natural extracellular matrix (ECM), but also because they can gelify in situ in seconds. Their mechanical properties can be fine-tuned to mimic natural tissues such as the nucleus pulposus (NP). This study produced different formula...
Tartrate-resistant acid phosphatase as a biomarker of bone turnover in dog
Sousa,C.P; Nery,F; Azevedo,J.T; Viegas,C.A; Gomes,M.E; Dias,I.RValues of serum tartrate-resistant acid phosphatase ( TRAP) activity were obtained in adult dogs and its biological variability was assessed. Nine healthy skeletally mature Portuguese Podengo dogs were used for the determination of TRAP, total and bone alkaline phosphatase serum activities, and also to study their relationship with serum minerals, namely calcium (Ca), phosphorous (P), and magnesium (Mg). The se...
Haematological and biochemical parameters in Churra-da-Terra-Quente ewes from t...
Dias,I.R.; Viegas,C.A.; Silva,A.M.; Pereira,H.F.; Sousa,C.P.; Carvalho,P.P.; Cabrita,A.S.; Fontes,P.J.; Silva,S.R.; Azevedo,J.M.T.Hematological and biochemical parameters, including plasma electrolytes and thyroid hormones, were determined in 73 clinically healthy Churra-da-Terra-Quente ewes, a typical breed from the northeast of Portugal. The hemogram values were: erythrocytes 9.8±1.5×10(12)/L; haemoglobin 118.1±19.1g/L; haematocrit 40.8±5.9%; leukocytes 5.7±1.8×10(9)/L; and platelets 544.3±177.2×10(9)/L. The thrombin time was 17.3±1.7 s...
Evaluating a bioremediation tool for atrazine contaminated soils in open soil m...
Lima, D.; Viana, P.; André, S.; Chelinho, S.; Costa, C.; Ribeiro, R.; Sousa, J. P.; Fialho, A. M.; Viegas, C. A.A previously developed potential cleanup tool for atrazine contaminated soils was evaluated in larger open soil microcosms for optimization under more realistic conditions, using a natural crop soil spiked with an atrazine commercial formulation (Atrazerba FL). The doses used were 20£ or 200£ higher than the recommended dose (RD) for an agricultural application, mimicking over-use or spill situations. Pseudomon...
Inspiratory flow-volume curve in snoring patients with and without obstructive ...
Amado,V.M.; Costa,A.C.G.A.; Guiot,M.; Viegas,C.A.; Tavares,P.We analyzed the flow-volume curves of 50 patients with complaints of snoring and daytime sleepiness in treatment at the Pneumology Unit of the University Hospital of Brasília. The total group was divided into snorers without obstructive sleep apnea (OSA) (N = 19) and snorers with OSA (N = 31); the patients with OSA were subdivided into two groups according to the apnea/hypopnea index (AHI): AHI<20/h (N = 14)...
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