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Effect of mannan oligosaccharides on the performance, intestinal morphology and...

A common problem in rabbits is the occurrence of digestive disorders just after weaning. This problem is associated with instability of the cecal microflora and characterized by diarrhea, loss of appetite and increased mortality. In the current study the effects of mannan oligosaccharide (MOS, Bio-Mos®, Alltech Inc., USA), a natural growth promoter, were compared to a commonly used antibiotic growth promoter (A...

Taxonomic resolution and Biological Traits Analysis (BTA) approaches in estuari...

The taxonomic and functional structure of the subtidal nematode assemblages from a temperate estuary (Mondego estuary, Portugal) was studied, focussing on different taxonomic levels (genus, family and order), on single functional groups and on multiple biological traits. Based on taxonomic levels and on four biological traits (feeding type, life strategy, tail and body shape), the analysis of the nematode assem...

ApoB/ApoA1 ratio improves clinical criteria sensitivity for the identification ...

Prémio de melhor poster.

Vacuolar cells seem to be a special trait of the esophagus and crop of carnivor...

Vacuolar cells seem to be a special trait of the esophagus and crop of carnivor...

Protein networks related to familial hypercholesterolemia gene

Familial hypercholesterolemia (FH) results mainly from defects in the hepatic uptake and degradation of LDL via the LDL-receptor pathway, commonly caused by a lossof-function mutation in the LDLR receptor gene (LDLR) or mutations in the gene coding apolipoprotein B (APOB) or rare dominant gain-of-function mutations in a member of the pro-protein convertase family (PCSK9). However, mutations which encode a prote...

Pathogenicity assessment of LDLR variants in patients with Familial Hypercholes...

Mutations in LDLR gene are the major cause of Familial Hypercholesterolemia (FH) but there are several variants described whose pathogenicity is still unknown. To date 88 different mutations in LDLR have been identified in the Portuguese population most of them, although being present in other populations, don’t have functional studies reported. A previous work recently reported by our group investigated the pa...

APOB: old gene, new perspective for Familial Hypercholesterolaemia

Familial hypercholesterolemia (FH) is one of the most common diseases of lipid metabolism, has an autosomal dominant inheritance and was the first genetic disorder of lipid metabolism to be characterized molecularly. FH usually results from inherited defects in the low density lipoprotein receptor (LDLR) gene and is characterised by increased circulating low density lipoprotein (LDL) cholesterol that leads to l...

Pathogenicity assessment of LDLR variant: a contribution for the correct manage...

Novas mutações funcionais no gene APOB causam hipercolesterolemia Familiar