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Phase II study on paclitaxel in patients with recurrent, metastatic or locally ...

Witteveen, PO; van der Velden, J; Vergote, I; Guerra, C; Scarabeli, C; Demonty, G; Reed, N

BACKGROUND: No standard treatment options are available for patients with advanced, recurrent or metastatic vulvar carcinoma not amenable for locoregional treatment. PATIENTS AND METHODS: In this phase II study, patients with advanced vulvar cancer received paclitaxel (Taxol) every 3 weeks for up to 10 cycles. Primary objective was response rate. Secondary objectives were response duration and toxicity. Respons...


Classification of radical hysterectomy adopted by the Gynecological Cancer Grou...

Mota, F; Vergote, I; Trimbos, JB; Amant, F; Siddiqui, N; Del Rio, A; Verheijen, R; Zola, P

The Piver classification of radical hysterectomy for the treatment of cervical cancer is outdated and misused. The Surgery Committee of the Gynecological Cancer Group of the European Organization for Research and Treatment of Cancer (EORTC) produced, approved, and adopted a revised classification. It is hoped that at least within the EORTC participating centers, a standardization of procedures is achieved. The ...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia