In the southern sector of the Ossa-Morena Zone (Iberian Variscan Chain), along its boundaries with the Beja-Acebuches Ophiolite and the South-Portuguese Zone, Upper Palaeozoic igneous mafic and intermediate rocks, both intrusive and extrusive, are widely represented. The so-called Odivelas Unit (Andrade,1983), include (meta-) basalts and (meta-) andesites, which, according with previous studies, display low-K ...
Infant acute lymphoblastic leukemia (IALL) is characterized by mixed lineage leukemia (MLL) gene rearrangements, unique gene expression profiles, poor prognosis, and drug resistance. One exception is cytosine arabinoside (Ara-C) to which IALL cells seem to be more sensitive. We quantified mRNA expression of Ara-C key enzymes in leukemic lymphoblasts from 64 Brazilian ALL children, 15 of them presenting MLL gene...
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