Tese de doutoramento, Medicina (Neurologia), Universidade de Lisboa, Faculdade de Medicina, 2013 ; Cerebral age-related white matter changes (WMC) designate the changes of the radiological appearance of cerebral white matter, detected either in CT scan or in MRI, of probable vascular aetiology, that are frequently described in elderly people (1,2,3). The clinical significance of those changes has gained attent...
This work was supported by Fundação Astrazeneca through the “Programa de Apoio à Investigação” . Presented at the “International Conference in Alzheimer’s Disease 2009 ; The distinction between normal aging and Alzheimer's disease (AD) is a relevant step to combat this disease efficiently. Thus, the identification of biomarkers and genetic factors underlying AD pathology is extremely important. Oxidative injur...
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