Biodiesel, in the form of fatty acid esters, produced by oleaginous microorganisms, could represent an attractive alternative of renewable liquid biofuels. Lipid metabolism has been studied extensively in S. cerevisiae and all genes encoding enzymes directly involved in lipid synthesis are known. In this model yeast, exogenous long-chain fatty acids are activated to coenzyme A derivatives prior to metabolic uti...
Biodiesel, in the form of fatty acid esters, produced by oleaginous microorganisms, could represent an attractive alternative of renewable liquid biofuels. In the model yeast S. Cerevisiae lipid metabolism has been studied extensively and all genes encoding enzymes directly involved in lipid synthesis are known. In this organism exogenous long-chain fatty acids are activated to coenzyme A derivatives prior to m...
The S. cerevisiae membrane protein Jen1 is a monocarboxylate-proton symporter which after the addition of glucose to lactic acid-grown cells triggers loss of Jen1p activity and repression of JEN1 gene expression (Paiva et al., 2002; Andrade et al., 2001). This downregulation of the permease is dependent on phosphorylation and ubiquitylation mechanisms, both of which are dependent on proteins interacting with th...
Biocerâmicas porosas têm sido utilizadas como suporte para crescimento de células ósseas por guiarem o crescimento celular, mimetizando a matriz extracelular e outras moléculas biológicas, o que facilita a formação de tecidos e órgãos funcionais. Fosfatos de cálcio são conhecidos pela sua grande similaridade química e morfológica com a parte mineral dos tecidos ósseos. Essa similaridade permite a osteocondução,...
[Abstract] ; [Resumo]
Production of renewable liquid biofuels that can substitute fossil fuel, has emerged as a major challenge for applied biology. Biodiesel, in the form of fatty acid esters, produced by oleaginous microorganisms could be an attractive alternative, since the utilization of diesel fuel is more efficient than for example ethanol. Oleaginous algae and yeasts may accumulate very high (60%) levels of intracellular lipi...
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