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Co-expression of monocarboxylate transporter 1 (MCT1) and its chaperone (CD147)...

Oliveira, Antônio Talvane Torres; Pinheiro, Céline; Filho, A. L.; Brito, Maria José; Martinho, Olga; Matos, Delcio; Carvalho, André Lopes

Antônio Talvane Torres de Oliveira and Céline Pinheiro contributed equally to the study ; Prova tipográfica (uncorrected proof) ; Monocarboxylate transporters (MCTs) have been described to play an important role in cancer, but to date there are no reports on the significance of MCT expression in gastrointestinal stromal tumors (GISTs). The aim of the present work was to assess the value of MCT expression, as ...


Opportunistic screening for skin cancer using a mobile unit in Brazil

Mauad, Edmundo C.; Silva, Thiago Buosi; Latorre, Maria RDO; Vieira, René AC; Haikel Junior, Raphael L.; Vazquez, Vinícius Lima; Longatto Filho, Adhemar

Background: Skin cancer is the most common malignancy in the white population worldwide. In Brazil, the National Cancer Institute (INCA) estimates that in 2010 there will be 119,780 and 5,930 new cases of nonmelanoma skin cancer and melanoma, respectively. The aim of this study was to evaluate the use of a mobile unit in the diagnosis and treatment of skin cancer in several poor regions of Brazil. Methods: The ...


Lymphangiogenic VEGF-C and VEGFR-3 expression in genetically characterised gast...

Oliveira, Antônio Talvane Torres; Reis, R. M.; Afonso, Julieta; Martinho, Olga; Matos, Delcio; Carvalho, André Lopes; Vazquez, Vinícius Lima

This study aimed to assess the distribution of VEGF-C and VEGFR-3 expression in gastrointestinal stromal tumours (GISTs), and to analyse the value of lymphatic vessel density (LVD) in a tumour that is believed to preferentially metastasize through blood vessel conduits. A panel of immunohistochemical antibodies was used to evaluate 51 cases of genetically characterised GISTs: VEGF-C, VEGFR-3, D2-40 (for LVD ass...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia