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Cocaine: historical background, neurobiology of the addiction and relapse and t...

Silva, M I; Citó, M C; Vasconcelos, P F; Vasconcelos, S M; Sousa, F C

Following more than a century of cocaine hydrochloride extraction from Erythroxylon coca, this drug remains representing a serious social and public health problema around the world. This paper intends to provide a review about the cocaine theme, focusing on historical background and on its different neurotransmission systems, as well as addresses therapeutics aspects about drug addiction.Electronic search in d...

Data: 2010   |   Origem: Acta Médica Portuguesa

Hibridização genômica in situ em triticeae: um enfoque metodológico.

BRAMMER, S. P.; POERSCH, L. B.; OLIVEIRA, A. R. de; VASCONCELOS, S.; BRASILEIRO-VIDAL, A. C.

2009

Data: 2009   |   Origem: OASIS br

Scientist-friendly policies for non-native English-speaking authors: timely and...

Vasconcelos,S.M.R.; Sorenson,M.M.; Leta,J.

That English is the lingua franca of today's science is an indisputable fact. Publication in English in international journals is a pre-requisite for a research paper to gain visibility in academia. However, English proficiency appears to be taken for granted in the scientific community, though this language can be a hurdle for a number of authors, particularly from non-native English-speaking countries. The in...

Data: 2007   |   Origem: OASIS br

Effects of chronic ethanol treatment on monoamine levels in rat hippocampus and...

Vasconcelos,S.M.M.; Cavalcante,R.A.; Aguiar,L.M.V.; Sousa,F.C.F.; Fonteles,M.M.F.; Viana,G.S.B.

We studied the effects of ethanol on concentrations of noradrenaline (NE), dopamine (DA) and serotonin (5-HT) and their metabolites in rat hippocampus and striatum. Ethanol (2 or 4 g/kg, po, from a 20% aqueous solution) was administered daily to male Wistar rats (4-13 per group) for 30 days and animals were sacrificed 30 min or 48 h after the last administration. Monoamines were measured by HPLC and considered ...

Data: 2004   |   Origem: OASIS br

Effect of one-week ethanol treatment on monoamine levels and dopaminergic recep...

Vasconcelos,S.M.M.; Macêdo,D.S.; Lima,L.O.; Sousa,F.C.F.; Fonteles,M.M.F.; Viana,G.S.B.

We studied the effects of ethanol on the levels of norepinephrine, dopamine, serotonin (5-HT) and their metabolites as well as on D1- and D2-like receptors in the rat striatum. Ethanol (2 or 4 g/kg, po) was administered daily by gavage to male Wistar rats and on the 7th day, 30 min or 48 h after drug administration, the striatum was dissected for biochemical assays. Monoamine and metabolite concentrations were ...

Data: 2003   |   Origem: OASIS br

Substratos para germinação de sementes de café.

PEREIRA, R. de C. A.; VASCONCELOS, S. S. de; SALES, F. de.

2000

Data: 2000   |   Origem: OASIS br

Effect of selenium supplementation on some blood biochemical parameters in male...

Crespo, A.M.V.; Lança, M.J.; Vasconcelos, S.; Andrade, V.; Rodrigues, H.; Santos, M.C.

The long-term effect of selenium supplementation on blood glutathione peroxidase (GSH-Px) activity and plasma TBARS’ production (as an index of peroxidation) was evaluated in 15-mo-old male rats fed a diet supplemented with 0.25 or 0.50 ppm selenium, for 12 mo. A group of nonsupplemented age-matched rats was the control. In addition, triglycerides, phospholipids, total and free cholesterol, HDL-cholesterol, and...


The effect of age and selenium on some biochemical parameters in rat liver

Santos, M.C.; Rodrigues, H.; Vasconcelos, S.; Andrade, V.; Lança, M.J.; Crespo, A.M.V.

Two age groups, 3 and 15 mo, were used to investigate whether age-associated changes in some parameters related to lipid peroxidation occur in the liver of male Wistar rats and to observe possible effects of dietary selenium supplementation (0.25 and 0.50 ppm) for 12 mo on the same parameters. At these experimental conditions, the most important observation was that peroxidation did not change by aging, at leas...


The effect of age and selenium on some biochemical parameters in rat liver

Santos, M.C.; Rodrigues, H.; Vasconcelos, S.; Lança, M.J.; Andrade, V.; Crespo, A,M,V,

Two age groups, 3 and 15 mo, were used to investigate whether age-associated changes in some parameters related to lipid peroxidation occur in the liver of male Wistar rats and to observe possible effects of dietary selenium supplementation (0.25 and 0.50 ppm) for 12 mo on the same parameters. At these experimental conditions, the most important observation was that peroxidation did not change by aging, at leas...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia