Encontrados 9 documentos, a visualizar página 1 de 1
A single intraperitoneal injection of ketamine does not affect spatial working ...
Ribeiro, Patrícia; Rodrigues, Paula; Valentim, Ana; Antunes, LuísCONTEXT: Ketamine is an anaesthetic and analgesic drug used in research and clinical practice. Little is known about the effects of different doses of this drug on memory and brain cellular death. OBJECTIVE: To study the effects of different doses of ketamine on working and reference memory, and neurodegeneration in adult mice. DESIGN: A randomised study. SETTINGS: The study was carried out in a basic scien...
Apoptotic neurodegeneration and spatial memory are not affected by sedative an...
Ribeiro, Patrícia; Valentim, Ana; Rodrigues, Paula; Olsson, Anna; Antunes, LuísBackground. Ketamine is increasingly popular in clinical practice and its combination with a 2-agonists can provide good anaesthetic stability. Little is known about the effects of this combination in the brain. Therefore, we investigated the effects of different concentrations of ketamine combined with medetomidine on cognition and its potential apoptotic neurodegenerative effect in adult mice. Methods. Sevent...
Behavioural effects of anaesthetics-risk of cognitive alterations.
Valentim, Ana Maria MarquesDoutoramento em Ciências Veterinárias ; Doctoral Degree in Veterinary Sciences
Different Concentrations of Ketamine did not Affect Cognition or Neurodegenerat...
Ribeiro, Patrícia; Valentim, Ana; Rodrigues, Paula; Antunes, LuísBackground: Ketamine is used in clinic how anesthetic and analgesic agent (1). However, little is known about the effects of the acute administration of this drug in brain of adult mice. The aim of this work was to study the effect of different concentrations of ketamine on cognition and its neurodegenerative effects. Methods: Forty-eight mice males, inbred C57BL/6, with 28 weeks old, were divided into 4 diffe...
Lower isoflurane concentration affects spatial learning and neurodegeneration i...
Valentim, Ana; Giminiani, Pierpaolo; Ribeiro, Patrícia; Rodrigues, Paula; Olsson, Ana; Antunes, LuísBackground: Volatile anesthetics such as isoflurane are widely used in clinical and research contexts. Concerns have been raised that the effects of these drugs on the central nervous system may result in long-term impairment after surgery or general anesthesia. Hence, this study aimed to detect how different isoflurane concentrations influence spatial learning and cell death in adult mice. Methods: Fifty-two C...
Cognitive and neurodegenerative effects of the ketamine/medetomidine anesthesia...
Ribeiro, Patrícia; Valentim, Ana; Rodrigues, Paula; Olsson, Anna; Antunes, LuísFCT - Portugal (PTDC/CVT099022/2008 and SFRH/BD/488)
Cognitive and Neurodegenerative Effects of the Medetomidine/Ketamine Anesthesia...
Ribeiro, Patrícia; Valentim, Ana; Rodrigues, Paula; Antunes, LuísBackground: Medetomidine (MED)/Ketamine (KET) is a commonly used combination in laboratory animals. Several studies have shown that KET can enhance neuronal death in neonates (1). Nerveless, little is known about its effect in combination with Med and in adult. The aim of this work was to study the effect of different concentrations of MED/KET in cognition and its potential neurodegenerative effect in adult mic...
Análise farmacogenómica de efeitos secundários da analgesia epidural com morfin...
Valentim, Ana do Rosário CaleiroO tratamento da dor pós-cesariana é essencial para a recuperação precoce e a longo prazo da puérpera. No entanto, coloca desafios adicionais aos médicos, porque existem diferenças entre a população obstétrica e a população cirúrgica geral, especificamente por causa dos receios da exposição do recém-nascido aos analgésicos administrados à mãe, além de que é desejável uma autonomia precoce e mobilização da puérpe...
Are seawalls made of natural substrata better?
Valentim, Ana L.; Martins, Gustavo M.; Neto, Ana I.International Meeting on Marine Resourses. Peniche, Portugal, 16-18 de Novembro de 2009.
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||