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Characterization of monocarboxylate transporters (MCTs) expression in soft tiss...
Pinheiro, Céline; Penna, Valter; Santos, Filipa Morais; Abrahão-Machado, Lucas F.; Ribeiro, Guilherme; Curcelli, Emílio C.; Olivieri, Marcus V.Background: Soft tissue sarcomas (STSs) are a group of neoplasms, which, despite current therapeutic advances, still confer a poor outcome to half of the patients. As other solid tumors, STSs exhibit high glucose consumption rates, associated with worse prognosis and therapeutic response. As highly glycolytic tumors, we hypothesized that sarcomas should present an increased expression of lactate transporters (M...
Portuguese propolis disturbs glycolytic metabolism of human colorectal cancer i...
Santos, Luísa Filipa Morais dos; Gonçalves, Vera Mónica Miranda; Baltazar, Fátima; Valença, Isabel; Ferreira, Ana Margarida; Aguiar, Cristina AlmeidaPortuguese propolis disturbs glycolytic metabolism of human colorectal cancer in vitro ; Propolis is a resin collected by bees from plant buds and exudates, which is further processed through the activity of bee enzymes. Propolis has been shown to possess many biological and pharmacological properties, such as antimicrobial, antioxidant, immunostimulant and antitumor activities. Due to this bioactivity profile...
Search for portuguese propolis antimicrobial activity in a wide range of microo...
Valença, Isabel; Cunha, Ana; Baltazar, Fátima; Aguiar, CristinaPropolis is a bee product composed by several compounds such as waxes, resins, essential oils and other organic compounds. Over the last decades, several studies have shown a wide range of biological and pharmacological properties for propolis from different provenance. Due to this large spectrum of bioactivities, such as antimicrobial, antioxidant, anti-inflammatory, and antitumor, among others, this product c...
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