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Cholesterol affects African swine fever virus infection
Bernardes, C.; António, A.; Pedroso de Lima, Maria C.; Valdeira, M. L.African swine fever virus (ASFV) enters cells by receptor mediated endocytosis and requires a fusion event between the viral envelope and the limiting membrane of the endosome at low pH. In order to investigate the role of cholesterol in the early stages of ASFV infection, we have studied the effect of the removal of cell and viral membrane cholesterol by cholesterol oxidase treatment of cells and virions, as w...
Data: 1998
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Origem: Estudo Geral - Universidade de Coimbra
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