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Geographic distribution of methyltransferases of Helicobacter pylori: evidence ...

Vale, Filipa; Mégraud, Francis; Vítor, Jorge M. B.

Background Helicobacter pylori colonizes the human stomach and is associated with gastritis, peptic ulcer, and gastric cancer. This ubiquitous association between H. pylori and humans is thought to be present since the origin of modern humans. The H. pylori genome encodes for an exceptional number of restriction and modifications (R-M) systems. To evaluate if R-M systems are an adequate tool to determine the ge...


A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucl...

Roberts, Richard J.; Belfort, Marlene; Bestor, Timothy; Bhagwat, Ashok S.; Bickle, Thomas A.; Bitinaite, Jurate; Vítor, Jorge M. B.

A nomenclature is described for restriction endonucleases, DNA methyltransferases, homing endonucleases and related genes and gene products. It provides explicit categories for the many different Type II enzymes now identi®ed and provides a system for naming the putative genes found by sequence analysis of microbial genomes.


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia