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Performance of 3 methods for quality control for gynecologic cytology diagnoses
Utagawa, Maria Lúcia; Shirata, Neuza Kasumi; Ferraz, Maria da Gloria Mattosinho de Castro; Loreto, Celso di; Dall’ Agnol, Miria; Longatto Filho, AdhemarProva tipográfica (In Press)
Whole, turret and step methods of rapid rescreening : is there any difference i...
Montemor, Eliana Borin Lopes; Roteli-Martins, C.; Zeferino, Luiz Carlos; Amaral, Rita Goreti; Fonsechi-Carvasan, Gislaine AparecidaWe compared the performance of the Whole, Turret and Step techniques of 100% rapid rescreening (RR) in detection of falsenegatives in cervical cytology. We tested RR performance with cytologists trained and among those without training. We revised 1,000 consecutive slides from women participating in an ongoing international screening trial. Two teams of experienced cytologists performed the RR techniques: one t...
Screening for cervical Cancer in high-risk populations : DNA pap test or hybrid...
Pereira, Sónia Maria Miranda; Castelo, A.; Makabe, Sérgio; Utagawa, Maria Lúcia; Loreto, Celso di; Maeda, Marina Yoshiê Sakamoto; Marques, José A.This study was designed to evaluate whether Hybrid Capture II (HC2) test alone refer women to colposcopy as appropriately as DNA Papanicolaou (Pap) test, in the context of a high-risk group of women using the recently validated DNACitoliq LBC system. Women with suspected cervical disease were included in this crosssectional study at a tertiary center in São Paulo, Brazil, for further workup. All women had cervi...
O impacto do diagnóstico citológico de atipiasi indeterminadas no sistema públi...
Pereira, Sónia Maria Miranda; Yamamoto, Luzia S. U.; Loreto, Celso di; Silva, Luciana A.; Makabe, Sérgio; Marques, João A.As alterações citológicas de significado indeterminado representam uma importante limitação diagnóstica nos programas de escrutíneo de lesões cérvico-vaginais. A introdução de métodos biomoleculares, como o sistema de captura híbrida para detecção de HPV de alto risco contribui para a otimização da conduta clínica dessas pacientes, indicando colposcopia com precisão. Objetivo: avaliar o significado de lesões de...
Immunocytochemical expression of p16 INK4A and Ki-67 in cytologically negative ...
Longatto Filho, Adhemar; Utagawa, Maria Lúcia; Shirata, Neuza Kasumi; Pereira, Sónia Maria Miranda; Namiyama, Gislene; Kanamura, Cristina TakamiThis study was designed to analyze the cross-sectional comparison of the p16 INK4A and Ki-67 immunocytochemical expression in negative and equivocal (atyp-ical squamous cells of undetermined significance (ASC-US)) liquid-based cytology (LBC) samples testing positive for high-risk human papillomavirus (HPV) types with HC2 assay or polymerase-chain reaction (PCR). A series of 199 consecutive LBC speci-mens derive...
DCS liquid-based system is more effective than conventional smears to diagnosis...
Longatto Filho, Adhemar; Pereira, Sónia Maria Miranda; Loreto, Celso di; Utagawa, Maria Lúcia; Makabe, Sérgio; Maeda, Marina Yoshiê SakamotoObjective. To compare the performances of Papanicolaou test (PapTest) and of a new liquid-based cytology method, DNA-CitoliqR System (DCS), in a high-risk population, with histology confirmation. Methods. Paired specimens of exfoliated cervical cells were collected under split-sample protocol. All patients were submitted to colposcopy and a biopsy taken when any atypical transformation zone was seen. Sensitivit...
A morphological protocol and guide-list on uterine cervix cytology associated t...
Yamamoto,Luzia Setuko Umeda; Alves,Venâncio Avancini Ferreira; Maeda,Marina Yoshiê Sakamoto; Longatto-Filho,Adhemar; Utagawa,Maria Lucia; Eluf Neto,JoséThe present study was designed to further assess the validity of the cytological description of morphological lesions said to be related to Papillomavirus (HPV) infections in senior women. The casuistic comprised 196 cervical smears from a group of women with no clinical or morphological evidence of neoplasia, collected simultaneously with samples submitted to detection of HPV DNA by PCR in a previous study. Th...
A morphological protocol and guide-list on uterine cervix cytology associated t...
Yamamoto, Luzia S. U.; Alves, Venâncio Avancini Ferreira; Maeda, Marina Yoshiê Sakamoto; Longatto Filho, Adhemar; Utagawa, Maria Lúcia; Eluf Neto, JoséThe present study was designed to further assess the validity of the cytological description of morphological lesions said to be related to Papillomavirus (HPV) infections in senior women. The casuistic comprised 196 cervical smears from a group of women with no clinical or morphological evidence of neoplasia, collected simultaneously with samples submitted to detection of HPV DNA by PCR in a previous study. Th...
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