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Pheno-metabolomics characterization of a Saccharomyces cerevisiae strain collec...

Duarte, Ricardo Franco; Umek, Lan; Mendes, Inês; Castro, C. C.; Silva, João; Martins, R.; Ferreira, A. C. S.; Zupan, Blaz; Schuller, Dorit


Pheno-metabolomics characterization of a saccharomyces cerevisiae strain collec...

Franco-Duarte, Ricardo; Umek, Lan; Mendes, Inês; Castro, Cristiana C.; Silva, João; Martins, Rosa; Ferreira, António C. Silva; Zupan, Blaz


Study of genetic and phenotypic relationships in a Saccharomyces cerevisiae str...

Duarte, Ricardo Franco; Mendes, Inês; Umek, Lan; Neves, J. Drumonde; Zupan, Blaz; Schuller, Dorit

Genome sequencing is essential to understand individual variation and to study the relationship between genotype and phenotype. Recently, large-scale sequencing projects of Saccharomyces cerevisiae revealed the existence of a few well defined lineages and some mosaics of that lineages, and suggested the occurrence of two domestication events during the history of association to human activities, one for sake st...


The phenotypic landscape of a Saccharomyces cerevisiae strain collection

Mendes, Inês; Duarte, Ricardo Franco; Umek, Lan; Fonseca, Elza; Neves, J. Drumonde; Dequin, Sylvie; Zupan, Blaz; Schuller, Dorit

Within our previous work [1] we developed computational models to predict strains with specific phenotypes (e.g. low ethanol resistance, growth at 30ºC and growth in media containing galactose, raffinose or urea) from microsatellite allelic patterns. The objective of the present work was to gain deeper understanding of the phenotypic diversity of a heterogeneous Saccharomyces cerevisiae strain collection, using...


Computational approaches for the genetic and phenotypic characterization of a S...

Duarte, Ricardo Franco; Umek, Lan; Zupan, Blaz; Schuller, Dorit

Within this study, we have used a set of computational techniques to relate the genotypes and phenotypes of natural populations of Saccharomyces cerevisiae, using allelic information from 11 microsatellite loci and results from 24 phenotypic tests. A group of 103 strains was obtained from a larger S. cerevisiae winemaking strain collection by clustering with self-organizing maps. These strains were further char...


The genetic and phenotypic characterization of a saccharomyces cerevisiae wine ...

Duarte, Ricardo Franco; Umek, Lan; Zupan, Blaz; Schuller, Dorit

The objective of the present study was to compare genetic and phenotypic variation of 103 Saccharomyces cerevisiae strains isolated from winemaking environments. We used bioinformatics approaches to identify genetically similary strains with specific phenotypes and to estimate a strain's biotechnological potential. A S. cerevisiae collection, comprising 440 strains that were obtained from winemaking environment...


Bioinformatic approaches for the genetic and phenotypic characterization of a S...

Duarte, Ricardo Franco; Umek, Lan; Zupan, Blaz; Schuller, Dorit

Painel apresentado por D. Schuller ; The objective of the present study was to compare genetic and phenotypic variation of 103 Saccharomyces cerevisiae strains isolated from winemaking environments. We used bioinformatics approaches to identify genetically similary strains with specific phenotypes and to estimate a strain's biotechnological potential. A S. cerevisiae collection, comprising 440 strains that w...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia