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DNA-based biosensor for the electrocatalytic determination of antioxidant capac...
Barroso, M. Fátima; de-los-Santos-Álvarez, N.; Lobo-Castañón, M. J.; Miranda-Ordieres, A. J.; Delerue-Matos, Cristina; Oliveira, M. Beatriz P. P.Reactive oxygen species (ROS) are produced as a consequence of normal aerobic metabolism and are able to induce DNA oxidative damage. At the cellular level, the evaluation of the protective effect of antioxidants can be achieved by examining the integrity of the DNA nucleobases using electrochemical techniques. Herein, the use of an adenine-rich oligonucleotide (dA21) adsorbed on carbon paste electrodes for the...
Data: 2011
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Origem: Repositório Científico do Instituto Politécnico do Porto
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