A doença celíaca (DC) tardiamente diagnosticada pode levar a um quadro de desnutrição grave. O seu tratamento limita-se à instituição de dieta isenta de glúten, aspecto nem sempre respeitado com rigor pelos doentes.O presente trabalho tem como principal objectivo avaliar o cumprimento da dieta e a sua repercussão nutricional em doentes celíacos. Foram incluídas 72 crianças que frequentam a consulta externa de G...
Introdução: A elevada frequência de utilização dos Serviços de Urgência Hospitalares pelos utentes, constitui um antigo, mas sempre actual, problema com que os Hospitais se deparam.No sentido de conhecer as motivações e práticas dos utentes do Serviço de Urgência de Pediatria do Hospital de São João realizámos um inquérito prospectivo.Material e Métodos: Foi realizado um inquérito prospectivo aos acompanhantes ...
Defined as an expectoration of blood from the subglottic airways, the hemoptysis is a symptom that suggests a variety of pathologies that can be more or less benign and even fatal, a life threatening for the person who suffers it. Between the most common causes we have bronchitis, bronchiectasis and bronchopulmonary neoplasia. Less frequent causes are: Goodpasture's syndrome, Wegener's granulomatosis, systemic ...
We describe, with a brief thematic review, the case of a 47-year-old woman that was hospitalized to study a clinical picture characterized by massive splenomegaly with asthenia, postprandial fullness, weight loss and edema in the left lower extremity, in which Gaucher disease was diagnosed. ; We describe, with a brief thematic review, the case of a 47-year-old woman that was hospitalized to study a clinical pi...
We have examined the role of cell surface glycosaminoglycans in cell division: adhesion and proliferation of Chinese hamster ovary (CHO) cells. We used both wild-type (CHO-K1) cells and a mutant (CHO-745) which is deficient in the synthesis of proteoglycans due to lack of activity of xylosyl transferase. Using different amounts of wild-type and mutant cells, little adhesion was observed in the presence of lamin...
The anticlotting and antithrombotic activities of heparin, heparan sulfate, low molecular weight heparins, heparin and heparin-like compounds from various sources used in clinical practice or under development are briefly reviewed. Heparin isolated from shrimp mimics the pharmacological activities of low molecular weight heparins. A heparan sulfate from Artemia franciscana and a dermatan sulfate from tuna fish ...
Fucans, a family of sulfated polysaccharides present in brown seaweed, have several biological activities. Their use as drugs would offer the advantage of no potential risk of contamination with viruses or particles such as prions. A fucan prepared from Spatoglossum schröederi was tested as a possible inhibitor of cell-matrix interactions using wild-type Chinese hamster ovary cells (CHO-K1) and the mutant type ...
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