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Long-term effects of tafamidis for the treatment of transthyretin familial amyl...

Coelho, T.; Maia, L.; Martins-Silva, A.; Cruz, M.; Planté-Bordeneuve, V.; Suhr, O.; Conceição, I.; Schmidt, H.; Trigo, P.; Kelly, J.; Labaudinière, R.

Tafamidis, a transthyretin (TTR) kinetic stabilizer, delayed neuropathic progression in patients with Val30Met TTR familial amyloid polyneuropathy (TTR-FAP) in an 18-month randomized controlled trial (study Fx-005). This 12-month, open-label extension study evaluated the long-term safety, tolerability, and efficacy of tafamidis 20 mg once daily in 86 patients who earlier received blinded treatment with tafamidi...


Distance ratio: an exploratory application to compare complex networks

Caseiro, N.; Trigo, P.

Books of Abastracts disponível em http://eccs2012.ulb.ac.be/media/eccs_handbook_web.pdf ; This paper describes an experimental application of the distance ratio measure used to compare individual networks among themselves and to analyze the aggregated network representing the group mental model from the field of emergency management. The data was obtained by surveying a group of Civil Protection graduates and ...


Comparing complex networks: An application to emergency managers mental models

Caseiro, N.; Trigo, P.

This paper describes an exploratory work that aims to identify a semantic basis underlying a mental model from the field of emergency management using a collaborative approach. An experimental application of the distance ratio measure was used to compare individual networks among themselves and to analyze the aggregated network representing the group mental model. The data was obtained by surveying a group of C...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia