Gene knockdown has emerged as an important tool for cancer gene therapy as well as for viral infections and dominantly inherited genetic disorders. The generation of suitable siRNA delivery systems poses some challenges, namely, to avoid nuclease degradation, to surpass the cytoplasmic membrane, and to release the nucleic acids into the cytosol. Aiming at evaluating the ability of thermoresponsive block copolym...
The in vivo adsorption of fluoxetine by a commercial activated carbon and a laboratory prepared activated carbon fibre were studied. The results showthat the carbon materials tested are not toxic toWistar rats and both materials had a high efficacy in the in vivo adsorption of fluoxetine preventing toxicity of the drug overdose administered to the animals.
Anexo
Financiadores do RCAAP | |||||||
![]() |
![]() |
![]() |
![]() |
![]() |
![]() |