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Role of glucose as a modulator of anabolic and catabolic gene expression in nor...
Rosa, SC; Rufino, AT; Judas, F; Tenreiro, CM; Lopes, MC; Mendes, AFCartilage matrix homeostasis involves a dynamic balance between numerous signals that modulate chondrocyte functions. This study aimed at elucidating the role of the extracellular glucose concentration in modulating anabolic and catabolic gene expression in normal and osteoarthritic (OA) human chondrocytes and its ability to modify the gene expression responses induced by pro-anabolic stimuli, namely Transformi...
Data: 2011
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Origem: Repositório do Centro Hospitalar e Universitário de Coimbra
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