Encontrados 19 documentos, a visualizar página 1 de 2
Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in...
Mega, Cristina; Vala, Helena; Rodrigues-Santos, Paulo; Oliveira, Jorge; Teixeira, Frederico; Fernandes, Rosa; Reis, Flávio; Lemos, Edite Teixeira deBackground: The purpose of this study was to investigate some of the possible mechanisms underlying the protective effects of a dipeptidyl peptidase IV (DPP-IV) inhibitor, sitagliptin, on pancreatic tissue in an animal model of type 2 diabetes mellitus (T2DM), the Zucker Diabetic Fatty (ZDF) rat, focusing on glycaemic, insulinic and lipidic profiles, as well as, on apoptosis, inflammation, angiogenesis and prol...
Cálculo de doses em exames de TC abdómen-pélvico em dois hospitais da região de...
Umbelino, Tânia; Silva, Tatiana; Teixeira, Frederico; Mendes, LuísEste trabalho tem como objectivo avaliar se os valores de dose recebida pelos doentes que realizam exames de Tomografia Computorizada (TC) Abdómen-pélvicos em dois hospitais da grande Lisboa estão de acordo com os Níveis de Referência de Diagnóstico Europeus (NRD). Foram comparadas também as unidades dosimétricas de exames realizados com corrente modelada e de exames realizados com corrente contínua em ambos os...
Effect of recombinant human erythropoietin in a rat model of moderate chronic r...
Garrido, P.; Reis, Flávio; Costa, Elísio; Almeida, A.; Parada, B.; Teixeira-Lemos, E.; Santos, P.; Alves, R.; Sereno, J.; Pinto, R.; Tavares, C. A.Background/Aims: Chronic renal failure (CRF) patients develop anaemia, thus promoting cardiovascular complications, which seems to be favoured by the low kidney erythropoietin (EPO) production. The renal insufficiency degree might determine the moment to start recombinant human EPO (rhEPO) therapy. It has been attributed important non-hematopoietic effects to rhEPO, which might underlie cardio and renoprotectio...
Hepcidin serum levels and resistance to recombinant human erythropoietin therap...
Costa, Elísio; Swinkels, Dorine W.; Laarakkers, Coby M.; Rocha-Pereira, Petronila; Rocha, Susana; Reis, Flávio; Teixeira, Frederico; Miranda, VascoThis title was also presented orally at Clinical Biochemistry workshop,Faro, 29 Janeiro, 2010
Erythropoietin promotes deleterious cardiovascular effects and mortality risk i...
Piloto, Nuno; Teixeira, Helena M.; Teixeira-Lemos, Edite; Parada, Belmiro; Garrido, Patrícia; Sereno, José; Pinto, Rui; Carvalho, Lina; Costa, ElísioAthletes who abuse recombinant human erythropoietin (rhEPO) consider only the benefit to performance and usually ignore the potential short and long-term liabilities. Elevated haematocrit and dehydratation associated with intense exercise may reveal undetected cardiovascular risk, but the mechanisms underlying it remain to be fully explained. This study aimed to evaluate the cardiovascular effects of rhEPO in r...
Resistance to recombinant human erythropoietin therapy in haemodialysis patients
Costa, Elísio; Lima, Margarida; Rocha, Susana; Pereira, Petronila Rocha; Reis, Flávio; Castro, Elisabeth; Teixeira, Frederico; Miranda, VascoTo better clarify the mechanism of resistance to recombinan thuman erythropoietin (rhEPO) therapy in haemodialysis patients, we studied systemic changes associated with resistance to rhEPO therapy in haemodialysis patients under rhEPO therapies, with particular interest on inflammation, leukocyte activation, iron status, oxidative stress and erythrocyte damage. We studied 63 chronic kidney disease (CKD) patient...
Higher fibrinolytic and inflammatory markers are associated with central venous...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Castro, Elisabeth; Reis, Flávio; Teixeira, Frederico; Miranda, Vasco; Faria, Maria Sameiro
DMT1 (NRAMP2/DCT1) genetic variability and resistance to recombinant human eryt...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Reis, Flávio; Castro, Elisabeth; Teixeira, Frederico; Miranda, Vasco; Faria, Maria do Sameiro
Cross-talk between inflammation, coagulation/fibrinolysis and vascular access i...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Castro, E.; Reis, Flávio; Teixeira, Frederico; Miranda, Vasco; Faria, Maria do SameiroThis work aimed to study the association between fibrinolytic/endothelial cell function and inflammatory markers in chronic kidney disease (CKD) patients undergoing hemodialysis (HD) and recombinant human erythropoietin (rhEPO) therapies, and its relationship with the type of vascular access (VA) used for the HD procedure. As fibrinolytic/endothelial cell function markers we evaluated plasminogen activator inhi...
Altered erythrocyte membrane band 3 profile in chronic renal failure patients u...
Costa, Elísio; Rocha, Susana; Rocha-Pereira, Petronila; Castro, Elisabeth; Reis, Flávio; Teixeira, Frederico; Miranda, Vasco; Sameiro-Faria, Maria
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