Encontrados 12 documentos, a visualizar página 1 de 2
Riscos e benefícios dos anti-inflamatórios não esteróides inibidores seletivos ...
Tavares, Tânia Isabel AlmeidaProjeto de Pós-Graduação/Dissertação apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de Mestre em Ciências Farmacêuticas. ; Os anti-inflamatórios não esteróides inibidores seletivos da ciclo-oxigenase-2 (Coxibes) são fármacos utilizados no tratamento da dor e inflamação crónica, principalmente em patologias de origem musculoesquelética, como a artrite reumatóide, oste...
Novel whey-derived peptides with inhibitory effect against angiotensin-converti...
Tavares, Tânia; Del Mar Contreras, Maria; Amorim, Manuela; Pintado, Manuela; Recio, Esidra; Malcata, F. XavierWhey protein concentrate (WPC) was subjected to enzymatic hydrolysis by proteases from the flowers of Cynara cardunculus, and the resulting angiotensin-converting enzyme (ACE)-inhibitory effect was monitored. The whole WPC hydrolysate exhibited an IC50 value of 52.9±2.9ºg/mL, whereas the associated peptide fraction with molecular weight below 3 kDa scored 23.6±1.1ºg/mL. The latter fraction was submitted to RP-H...
Distribuição espacial de compostos orgânicos de estanho em sedimentos costeiros...
Pletsch,Adelmo Lowe; Beretta,Magda; Tavares,Tania MascarenhasOrganic tin compounds were investigated in the sediment of twenty-four stations located in the Todos os Santos Bay and the north coast of Bahia - Brazil. The concentration of these organic tin was also determined in a ascidium species of Phallusia nigra. The speciation and quantification was performed by GC-MS/MS. The highest concentrations were: tributyltin (TBT) 438 ng g-1, dibutyltin (DBT) 207 ng g-1, monobu...
Development and analytical characterization of ofloxacin ion-selective electrodes
Souto, Renata; Pimenta, Adriana; Leal, Fernanda; Catarino, Rita; Santos, Gory; Tavares, TâniaAn ofloxacin-selective electrode based on incorporation of a ofloxacin-tetrakis[3,5- bis(trifluoromethyl)phenyl]borate ion-pair complex in a poly(vinyl chloride) membrane was developed. The sensor displayed a Nernstian response over a wide concentration range (7×10-6–1×10-2 mol L-1) with a slope of 54.9 ± 1.3 mV per decade of concentration, a detection limit of 4×10-6 mol L-1 and adequate selectivity toward som...
Contribution of coagulant and native microflora to the volatile-free fatty acid...
Tavaria, Freni K.; Tavares, Tânia G; Ferreira, A.C.Silva; Malcata, F. XavierThe contributions of the coagulant Cynara cardunculus and of the microflora of raw milk to the volatile-free fatty acid profile of Serra da Estrela cheese were evaluated. The experimental design included both a model system and, dual cheeses. The study in the model system showed that isovaleric acid was the predominant volatile compound after 7 d of ripening. The systems inoculated with Enterococcus faecium pro...
Laboratory validation of a passive sampler for SO2 atmospheric monitoring
Cruz,Lícia P. S.; Campos,Vânia P.; Novaes,Jussival A. P.; Tavares,Tania M.The performance of a passive sampler was tested under exposure in Teflon chamber. The SO2 trapped in impregnated filter with 1.0 x 10-2 mol L-1 Na2CO3 solution was extracted in ultrasound bath with H2O2 solution for 15 min and determined as SO4(2-) by ion chromatography. The sampler presented good performance except for air in total stillness condition (0 m s-1), for very short exposure periods (0.5 h), for atm...
Influence of native lactic acid bacteria on the microbiological, biochemical an...
Macedo, Angela C.; Tavares, Tânia G.; Malcata, F. XavierCheesemaking from batches of raw ewe’s milk was carried out via inoculation with wild strains of Lactococcus lactis subsp. lactis ESB110019 and Lactobacillus plantarum ESB5004 independently, or combined with each other. Those two strains had been isolated from the native microflora of typical Serra da Estrela cheese. One control batch was processed in parallel without addition of any starter. The evolution in v...
Esterase activities of intracellular extracts of wild strains of lactic acid ba...
Macedo, Angela C.; Tavares, Tânia G.; Malcata, F. XavierLactococcus lactis subsp. lactis strain ESB110019 and Lactobacillus plantarum strain ESB5004, novel strains that were previously isolated from the wild adventitious microflora of certified Serra da Estrela cheeses, were assayed for esterase activity using, as substrates, ortho- and para-nitrophenyl derivatives of fatty acids. Both strains preferentially hydrolyzed short-chain fatty acids; L. lactis ESB110019 ex...
Purification and characterization of an intracellular aminopeptidase from a wil...
Macedo, Angela C.; Tavares, Tânia G.; Malcata, F. XavierAn intracellular hydrolase able to cleave Image -lysine-p-nitroanilide was purified from Lactobacillus plantarum strain ESB5004 via two steps of precipitation with ammonium sulfate (at 30 and 50% (w/v)), followed by hydrophobic interaction and ion-exchange chromatographies. The aminopeptidase was purified up to 11-fold, with a final yield of ca. 1%. Its native molecular weight is ca. 70 kDa, and it is apparentl...
Comparação de dois tipos de amostragem de chuva: deposição total e deposição ap...
Campos,Vânia P.; Costa,Angela C. A.; Tavares,Tania M.In a tropical coastal area. During 6 months the composition of rain samples collected simultaneously over 24h with an open collector and with an automatic opened collector (KFA - J¸lich Type) at 500m of the Atlantic coastline of Salvador were compared. All average concentrations were higher for the "total" samples than for the "wet only" samples, except for hydrogen ions, nitrate and ammonium.
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