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Antileishmanial Drugs: search for t SIR2 inhibitors

Leishmaniasis is a parasitic disease, caused by the protozoa of the genus Leishmania that affects millions of people worldwide, especially in tropical and subtropical areas, and is responsible for high mortality and morbidity. Disease control is dependent on drug therapy, since no approved human vaccine is available. However, the existing therapy is far from satisfactory owing to the emergence of resistances, t...