To evaluate the performance of a new, manual, simplified liquid-based system, DNA-Citoliq (Digene Brasil), employed under routine conditions as compared to conventional smears collected from six collaborating private laboratories. Methods: A panel of cytopathologists, who served as the gold standard diagnosis, adjudicated discordant opinions. Results: Of 3206 pairs of slides considered valid for comparison, the...
Hybrid capture is an easy and highly sensitive technique for screening population due to its capacity to detect malignant and premalignant lesions of the cervix. To evaluate its ensitivity, we investigated the frequency of high-risk human papillomavirus (HPV) infection and its correlation with glandular malignant lesions, analyzing a total of 113 cases of adenocarcinomas and related lesions. High-risk HPV was ...
O HPV é causa essencial, mas não suficiente, para o desenvolvimento de lesões pré-neoplásicas e neoplásicas do colo uterino. Sua identificação é fundamental para a avaliação de risco, sendo que o método de Captura Híbrida® apresenta reconhecida eficácia para esse fim. Por sua vez, os métodos morfológicos, colposcopia, citologia e histopatologia, demonstram as alterações celulares e tissulares sugestivas da ação...
Introduction: DCS is a new liquid-base cytology system for cell collected in UCM. Objective: assess technical aspects of DCS under different pro-tocols. Methods: the first experiment was performed with 144 samples. After cervical scraping with Ayre spatula and endocervical brushing, the sample was immediately smeared on the slide and alcohol-fixed. The same brush with residual cells was used to scrap the ectoce...
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