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Starch-based microspheres produced by emulsion crosslinking with a potential me...

Malafaya, P. B.; Stappers, Frank; Reis, R. L.

This paper describes the development and characterization of starch microspheres for being used as drug delivery carriers in tissue engineering applications. The developed starch microspheres can be further loaded with specific growth factors and immobilized in scaffolds, or administrated separately with scaffolds. Furthermore and due to the processing conditions used, it is expected that these microspheres can...


Emulsion crosslinking as a new manufacturing route to produce hydroxylapatite p...

Malafaya, P. B.; Stappers, Frank; Reis, R. L.

Bioactive particulates with tailored resorption rates can be very useful on biomedical applications such as filling of bone and dentristy defects, carriers for controlled release of bioactive agents and reinforcement in polymer/bioceramic orthopaedic composites. The aim of the present study was to develop a new processing route to produce composite particulates based on hydroxylapatite (HA) and starch. The newly...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia