Fifteen years after the initial detection of Rickettsia slovaca in ticks in Portugal, 3 autochthonous cases of R. slovaca infection were diagnosed in humans. All patients had an eschar on the scalp and lymphadenopathy; 2 patients had facial edema. R. slovaca infection was confirmed by serologic testing, culture, and PCR.
Aim: The development of novel silk/nano-sized calcium phosphate (silk/nano-CaP) scaffolds with highly dispersed CaP nanoparticles in the silk fibroin (SF) matrix for bone tissue engineering. Materials & methods: Nano-CaP was incorporated in a concentrated aqueous SF solution (16 wt.%) by using an in situ synthesis method. The silk/nano-CaP scaffolds were then prepared through a combination of salt-leaching/ lyo...
One of the major scientific challenges that tissue engineering and regenerative medicine (TERM) faces to move from benchtop to bedside regards biomaterials development, despite the latest advances in polymer processing technologies. A variety of scaffolds processing techniques have been developed and include solvent casting and particles leaching, compression molding and particle leaching, thermally induced pha...
No presente artigo apresentamos a descrição das diferentes fases de desenho e desenvolvimento do protótipo Web “Atreve-te com o Scratch“, bem como a avaliação da sua usabilidade. Assim, expomos para cada teste realizado: os objetivos, a descrição, os métodos e as técnicas de recolha de dados; a amostra e o perfil da mesma; a síntese dos resultados e as recomendações. Foram efetuados os seguintes testes: explora...
Spine stabilization upon spinal cord injury (SCI) is a standard procedure in clinical practice, but rarely employed in experimental models. Moreover, the application of biodegradable biomaterials for this would come as an advantage as it would eliminate the presence of a nondegradable prosthesis within the vertebral bone. Therefore, in the present work, we propose the use of a new biodegradable device specifica...
Data Mining (DM) techniques have been successfully used in many fields and more recently also in geotechnics with good results in different applications. They are adequate as an advanced technique for analysing large and complex databases that can be built with geotechnical information within the framework of an overall process of Knowledge Discovery in Databases (KDD). A KDD process is carried out in the conte...
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