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Clinical and genetic factors predicting response to therapy in patients with Cr...

Cravo, Marília; Ferreira, Paula; Sousa, Patrícia; Moura-Santos, Paula; Velho, Sónia; Tavares, Lurdes; Deus, João Ramos; Ministro, Paula

Aim - To identify clinical and/or genetic predictors of response to several therapies in Crohn’s disease (CD) patients. Methods - We included 242 patients with CD (133 females) aged (mean ± standard deviation) 39 ± 12 years and a disease duration of 12 ± 8 years. The single-nucleotide polymorphisms (SNPs) studied were ABCB1 C3435T and G2677T/A, IL23R G1142A, C2370A, and G9T, CASP9 C93T, Fas G670A and LgC844T, a...


Communication as an expression of humanized end-of-life care: a systematic review

Veríssimo, Filipa; Sousa, Patrícia

Objective: to identify the communication strategies that promote the humanization of health care provided to adult/older adult patients hospitalized at the end of life. Method: systematic review carried out with primary studies from EBSCO, PubMed, CINAHL, MEDLINE, LILACS, Web of Knowledge, and B-On databases, and SciELO and Cochrane digital libraries, between November 2012 and January 2013, selected according t...


Valuing wind farms’ environmental impacts by geographical distance : a continge...

Botelho, Anabela; Pinto, Lígia; Sousa, Patrícia Cristina Cruz de

Wind energy is currently one the most important energy sources in the production of electricity. In this study, we use the CVM to elicit the monetary value attached to wind power’s environmental impacts from three different groups of individuals: local residents, residents in a nearby town, and residents outside the area of a wind farm located in Portugal, one of the top 10 countries in the world with the highe...


Contribuição ao estudo da mistura néon-azoto a baixas temperaturas

Sousa, Patrícia Tavares Coutinho Borges de

Dissertação para obtenção do Grau de Mestre em Engenharia Física

Data: 2012   |   Origem: Repositório Institucional da UNL

Entry flow of viscoelastic fluids at macro- and micro-scale

Sousa, Patrícia Catarina Saraiva de

Tese de doutoramento. Engenharia Química e Biológica. Faculdade de Engenharia. Universidade do Porto. 2010


Artefacts induced on c-type haem proteins by electrode surfaces

Sousa, Patrícia M. Paes de; Pauleta, Sofia R.; Gonçalves, M. Lurdes Simões; Pettigrew, Graham W.; Moura, Isabel; Moura, José J. G.

J Biol Inorg Chem (2011) 16:209–215 DOI 10.1007/s00775-010-0717-z ; In this work it is demonstrated that the characterization of c-type haem containing proteins by electrochemical techniques needs to be cautiously performed when using pyrolytic graphite electrodes. An altered form of the cytochromes, which has a redox potential 300 mV lower than that of the native state and displays peroxidatic activity, can b...

Data: 2011   |   Origem: Repositório Institucional da UNL

Is Nitric Oxide Decrease Observed with Naphthoquinones in LPS Stimulated RAW 26...

Brígida R. Pinho; Carla Sousa; Patrícia Valentão; Paula B. Andrade

The search of new anti-inflammatory drugs has been a current preoccupation, due to the need of effective drugs, with less adverse reactions than those used nowadays. Several naphthoquinones (plumbagin, naphthazarin, juglone, menadione, diosquinone and 1,4-naphthoquinone), plus p-hydroquinone and p-benzoquinone were evaluated for their ability to cause a reduction of nitric oxide (NO) production, when RAW 264.7 ...


Reação de laranjeiras-doces quanto à resistência a Guignardia citricarpa

Sousa,Patrícia Ferreira Cunha; Goes,Antonio de

O objetivo deste trabalho foi determinar o comportamento de variedades de laranjas-doces quanto à resistência a Guignardia citricarpa, agente causal da mancha preta dos citros (MPC). Os ensaios foram conduzidos em dois campos, nos municípios de Rincão e Tambaú, SP. As mudas foram formadas em viveiro localizado na Estação Experimental de Citricultura de Bebedouro-SP. Para tal, foram utilizadas borbulhas de plant...

Data: 2010   |   Origem: OASIS br

A new CuZ active form in the catalytic reduction of N2O by nitrous oxide reduct...

Dell’Acqua, Simone; Pauleta, Sofia R.; Sousa, Patrícia M. Paes de; Monzani, Enrico; Casella, Luigi; Moura, José J. G.; Moura, Isabel

J Biol Inorg Chem (2010) 15:967–976 DOI 10.1007/s00775-010-0658-6 ; The final step of bacterial denitrification, the two-electron reduction of N2O to N2, is catalyzed by a multi-copper enzyme named nitrous oxide reductase. The catalytic centre of this enzyme is a tetranuclear copper site called CuZ, unique in biological systems. The in vitro reconstruction of the activity requires a slow activation in the pres...

Data: 2010   |   Origem: Repositório Institucional da UNL

O Teatro e a Prisão

Sousa, Patrícia Joana Baptista

A presente dissertação visa a obtenção do grau de mestre em Serviço Social pelo Instituto Superior Miguel Torga. Intitulado o Teatro e a Prisão, o presente estudo centra-se numa abordagem exploratória da importância do teatro em meio prisional, no qual procurámos compreender e explicar quais os benefícios da actividade teatral para os reclusos que nela participam. Isto para verificarmos se as actividades socioc...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia