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Progression of retinopathy and alteration of the blood-retinal barrier in patie...
Cunha-Vaz, JG; Lobo, CL; Sousa, JC; Leite, E; Faria de Abreu, JRBACKGROUND: The study was carried out to evaluate the correlation between blood-retinal barrier (BRB) permeability and the progression of diabetic retinopathy (DR), defined by development of "need for photocoagulation", over a 7-year period by means of vitreous fluorometry (VF). METHODS: Forty type 2 diabetic patients with minimal or no retinopathy, aged 40-65 years (mean 53.9 + 7.3 years), were followed up pro...
Blood-retinal barrier permeability and its relation to progression of retinopat...
Cunha-Vaz, JG; Leite, E; Sousa, JC; Faria de Abreu, JRForty patients with late-onset diabetes (age at diagnosis 30 years or more) and minimal retinopathy as found by fundus photography were followed prospectively by repeated examination (baseline, 1 year, and 4 years). The study shows that early retinopathy changes are not permanent or invariably progressive. In the 1st year of follow-up microaneurysms worsened in 25%, improved in 10%, and remained stabilized in 6...
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