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Polymerase Chain Reaction Screening for Fungemia and/or Invasive Fungal Infecti...
Ribeiro, P; Costa, F; Monteiro, A; Caldas, J; Silva, M; Ferreira, G; Veiga, J; Sousa, MO; Viegas, MP; Santos, E; Gonçalves, AJ; Sousa, ABINTRODUCTION: Invasive fungal infections (IFIs) are a life-threatening complication in patients with hematologic malignancies, mainly in acute leukemia patients, following chemotherapy. IFI incidence is increasing, and associated mortality remains high due to unreliable diagnosis. Antifungal drugs are often limited by inadequate antimicrobial spectrum and side effects. Thus, the detection of circulating fungal ...
Candidemia in Acute Leukemia Patients
Ribeiro, P; Sousa, AB; Aveiro, F; Nunes, O; Fernandes, JP; Gouveia, JFungal infections are an important cause of morbidity and mortality in patients with acute leukemia (AL). Candidemia, once rare, is now a common nosocomial infection because of the intensity of chemotherapy, prolonged neutropenia, administration of broad-spectrum antibiotics and use of central venous catheters (CVC). We retrospectively identified patients treated for AL from 6/86 to 6/95 who also had candidemia...
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