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Doença Hemolítica Perinatal — Caso Clínico

A doença hemolítica perinatal resulta da passagem placentária de anticorpos do tipo IgG contra antigénios eritrocitários fetais, dando origem a hemólise. A incompatibilidade Rh(D) é a responsável por cerca de 94% casos. As incompatibilidades por antigénios atípicos (anti-c, anti-Kell) apesar de raras, dão origem a quadros graves.Os autores apresentam um caso clínico de isoimunização anti-c num prematuro, I° fil...

O recém nascido de extremo baixo peso. Estado aos 2-3 anos. Resultados do Regis...

Background: Children born before 32 weeks or very low birth weight have a high risk for neurodevelopmental impairment. Aim: To analyze the condition of extreme low birth infants (weighing 1000g or less), born in the years 2005 and 2006, and included in the Portuguese National Very Low Birth Weight Network. Results: A total of 163 children were evaluated, 49.1% of which were males with a mean gestational age 27 ...

O recém nascido de extremo baixo peso: estado aos 2-3 anos: resultados do Regis...

Introdução: As crianças que nascem antes das 32 semanas ou com peso inferior a 1500g apresentam um elevado risco de sequelas no seu neurodesenvolvimento. Objectivo: Analisar a situação do crescimento e desenvolvimento neurosensorial das crianças com peso igual ou inferior a 1000g nascidas nos anos de 2005 e 2006 incluídas no registo nacional do muito baixo peso. Resultados: Das 163 crianças avaliadas, 49,1% e...

Comparing small-footprint lidar and forest inventory data for single strata bio...

Current methods for accurately estimating vegetation biomass with remote sensing data require extensive, representative and time consuming field measurements to calibrate the sensor signal. In addition, such techniques focus on the topmost vegetation canopy and thus they are of little use over multi-layered forest ecosystems where the underneath strata hold considerable amounts of biomass. This work is the firs...

Prediction of one year mortality in extremely premature newborns using classifi...

mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma

CONTEXT: There are several genetic and molecular evidences suggesting dysregulation of the mammalian target of rapamycin (mTOR) pathway in thyroid neoplasia. Activation of the phosphatidylinositol-3-kinase/AKT pathway by RET/PTC and mutant RAS has already been demonstrated, but no data have been reported for the BRAF(V600E) mutation. OBJECTIVE: The aim of this study was to evaluate the activation pattern of the...

Biomass expansion factors for Eucalyptus globulus stands in Portugal

One of several procedures for estimating carbon stocks in forests is the estimation of tree or stand biomass based on forest inventory data. The two approaches normally used to convert field measurements of trees to stand biomass values are allometric biomass equations and biomass expansion factors (BEFs). BEFs are used in published National Forest Inventory results in which biomass is not estimated or as a com...

mTOR pathway overactivation in BRAF mutated papillary thyroid carcinoma

CONTEXT: There are several genetic and molecular evidences suggesting dysregulation of the mammalian target of rapamycin (mTOR) pathway in thyroid neoplasia. Activation of the phosphatidylinositol-3-kinase/AKT pathway by RET/PTC and mutant RAS has already been demonstrated, but no data have been reported for the BRAF(V600E) mutation. OBJECTIVE: The aim of this study was to evaluate the activation pattern of the...

Impact of pelvic radiotherapy on female sexuality

PURPOSE: To assess physical and psychological morbidity, sexual functioning and social and relationship satisfaction among women treated with pelvic radiotherapy. METHODS: Observational (case-control) study of 199 women: 98 submitted to pelvic radiotherapy for the treatment of uterine, rectal or anal cancers and 101 without a personal history of cancer and similar socio-demographic variables. These completed a...

Impact of EGFR genetic variants on glioma risk and patient outcome

BACKGROUND: The epidermal growth factor receptor (EGFR) regulates important cellular processes and is frequently implicated in human tumors. Three EGFR polymorphisms have been described as having a transcriptional regulatory function: two single-nucleotide polymorphisms in the essential promoter region, -216G/T and -191C/A, and a polymorphic (CA)(n) microsatellite sequence in intron 1. We aimed to elucidate the...