Encontrados 26 documentos, a visualizar página 1 de 3
Hydrogen peroxide sensing, signaling and regulation of transcription factors
Marinho, H. Susana; Real, Carla; Cyrne, Luísa; Soares, Helena; Antunes, FernandoThe regulatory mechanisms by which hydrogen peroxide (H2O2) modulates the activity of transcription factors in bacteria (OxyR and PerR), lower eukaryotes (Yap1, Maf1, Hsf1 and Msn2/4) and mammalian cells (AP-1, NRF2, CREB, HSF1, HIF-1, TP53, NF-κB, NOTCH, SP1 and SCREB-1) are reviewed. The complexity of regulatory networks increases throughout the phylogenetic tree, reaching a high level of complexity in mammal...
Non-coding RNAs: multi-tasking molecules in the cell
Gomes, Anita Q.; Nolasco, Sofia; Soares, HelenaIn the last years it has become increasingly clear that the mammalian transcriptome is highly complex and includes a large number of small non-coding RNAs (sncRNAs) and long noncoding RNAs (lncRNAs). Here we review the biogenesis pathways of the three classes of sncRNAs, namely short interfering RNAs (siRNAs), microRNAs (miRNAs) and PIWI-interacting RNAs (piRNAs). These ncRNAs have been extensively studied and ...
Cleanup of industrial effluents containing heavy metals: a new opportunity of v...
Soares, Eduardo V.; Soares, Helena M. V. M.Heavy metal pollution is a matter of concern in industrialised countries. Contrary to organic pollutants, heavy metals are not metabolically degraded. This fact has two main consequences: its bioremediation requires another strategy and heavy metals can be indefinitely recycled. Yeast cells of Saccharomyces cerevisiae are produced at high amounts as a by-product of brewing industry constituting a cheap raw mate...
Cleanup of industrial effluents containing heavy metals : a new opportunity of ...
Soares, Eduardo V.; Soares, Helena M. V. M.Heavy metal pollution is a matter of concern in industrialised countries. Contrary to organic pollutants, heavy metals are not metabolically degraded. This fact has two main consequences: its bioremediation requires another strategy and heavy metals can be indefinitely recycled. Yeast cells of Saccharomyces cerevisiae are produced at high amounts as a by-product of brewing industry constituting a cheap raw mate...
O contributo do voluntariado no apoio aos idosos sós e/ou dependentes do concel...
Soares, Helena Isabel Costa.O envelhecimento da população é uma realidade generalizada dos países desenvolvidos e apresenta-se como um desafio social e económico do maior interesse para grande parte desses países. Atualmente verifica-se um contexto de diminuição gradual da natalidade, aliada a um aumento da esperança média de vida ou da longevidade dos indivíduos. A junção destes dois fatores ao nível dos países desenvolvidos fará com que...
The expression of tubulin cofactor A (TBCA) is regulated by a noncoding antisen...
Nolasco, Sofia; Bellido, Javier; Gonçalves, João; Zabala, Juan Carlos; Soares, Helena; Tavares, AlexandraAbstract - Recently, long noncoding RNAs have emerged as pivotal molecules for the regulation of coding genes' expression. These molecules might result from antisense transcription of functional genes originating natural antisense transcripts (NATs) or from transcriptional active pseudogenes. TBCA interacts with β-tubulin and is involved in the folding and dimerization of new tubulin heterodimers, the building ...
Mob1: defining cell polarity for proper cell division
Tavares, Alexandra; Gonçalves, João; Florindo, Cláudia; Tavares, Álvaro A.; Soares, HelenaMob1 is a component of both the mitotic exit network and Hippo pathway, being required for cytokinesis, control of cell proliferation and apoptosis. Cell division accuracy is crucial in maintaining cell ploidy and genomic stability and relies on the correct establishment of the cell division axis, which is under the control of the cell's environment and its intrinsic polarity. The ciliate Tetrahymena thermophil...
Biomass conversion : cellobiose and methylcellobiose conversion
Soares, Helena Sofia Marques PintoTese de mestrado integrado. Engenharia Química. Faculdade de Engenharia. Universidade do Porto, Delft University of Technology. 2009
"The Chinese Phytotherapy: Oriental and Western Pathophysiological Aspects and ...
Soares, Helena Cristina MendesMedicina Tradicional Chinesa ; Master of Traditional Chinese Medicine
Trajecto percorrido pelas vitimas de violência nas relações de intimidade no Se...
Soares, Helena Alice Lobo Martins NogueiraMedicina ; Medicine
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