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ICI 182,780 has agonistic effects and synergizes with estradiol-17 beta in fish...
Pinto, Patricia; Singh, Pratap B.; Condeça, João B.; Teodósio, H. R.; Power, Deborah; Canario, Adelino V. M.ICI 182,780 (ICI) belongs to a new class of antiestrogens developed to be pure estrogen antagonists and, in additi on to its therapeutic use, it has been used to knock-out estrogen and estrogen receptor (ER) actions in several mammalian species. In the present study, the effects and mechanism of action of ICI were investigated in the teleost fish, sea bream (Sparus auratus). Three independent in vivo experimen...
Data: 2006
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Origem: Sapientia - Universidade do Algarve
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