Tese de mestrado. Biologia (Biologia Molecular e Genética). Universidade de Lisboa, Faculdade de Ciências, 2013 ; Embryonic Stem Cells(ESC) are undifferentiated cells derived from the blastocyst and are able to self-renew indefinitely in defined minimal conditions, in the presence of LIF, BMP4 and MEK/GSK3 inhibitors. Pluripotency is an ESC property regulated by a complex gene regulatory network (GRN) that hav...
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