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Chondroitin sulfate immobilization at the surface of electrospun nanofiber mesh...

Piai, Juliana Francis; Martins, Albino; Silva, Marta Alves da; Reis, R. L.; Muniz, Edvani Curti; Neves, N. M.

Aiming at improving the biocompatibility of biomaterial scaffolds, surface modification presents a way to preserve their mechanical properties and to improve the surface bioactivity. In this work, chondroitin sulfate (CS) was immobilized at the surface of electrospun poly(caprolactone) nanofiber meshes (PCL NFMs). The immobilization was performed with 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide (EDC)/N-hydro...


Coating of polyethylene medical devices

Silva, Marta Alves da

Tese de mestrado. Engenharia Biomédica. Faculdade de Engenharia. Universidade do Porto, Faculdade de Medicina Dentária. Universidade do Porto. 2008


Dynamic culture of osteogenic cells in biomimetically coated poly(caprolactone)...

Araújo, J. V.; Reis, C. Cunha; Rada, Tommaso; Silva, Marta Alves da; Gomes, Manuela E.; Yang, Y.; Ashammakhi, N.; Reis, R. L.; El-Haj, Alicia J.

In our previous work, biomimetic calcium phosphate-coated poly(caprolactone) nanofibre meshes (BCP-NMs) were demonstrated to be more effective for supporting cell attachment and proliferation under static conditions, when compared with poly(caprolactone) nanofibre meshes (PCL-NMs). In many applications, in vitro cultivation of constructs using bioreactors that support efficient nutrition of cells has appeared a...


Impact of biological agents and tissue engineering approaches on the treatment ...

Silva, Marta Alves da; Martins, Albino; Teixeira, A. A.; Reis, R. L.; Neves, N. M.

The treatment of rheumatic diseases has been the focus of many clinical studies aiming to achieve the best combination of drugs for symptom reduction. Although improved understanding of the pathophysiology of rheumatic diseases has led to the identification of effective therapeutic strategies, its cure remains unknown. Biological agents are a breakthrough in the treatment of these diseases. They proved to be mo...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia