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Involvement of yeast HSP90 isoforms in response to stress and cell death induce...
Silva, Maria Alexandra; Marques, Belém Sampaio; Fernandes, Ângela Margarida Oliveira; Carreto, Laura; Rodrigues, Fernando José dos SantosAcetic acid-induced apoptosis in yeast is accompanied by an impairment of the general protein synthesis machinery, yet paradoxically also by the up-regulation of the two isoforms of the heat shock protein 90 (HSP90) chaperone family, Hsc82p and Hsp82p. Herein, we show that impairment of cap-dependent translation initiation induced by acetic acid is caused by the phosphorylation and inactivation of eIF2 alpha by...
New insight into translation during yeast programmed cell death
Silva, Maria Alexandra Oliveira daTese de doutoramento em Ciências da Saúde ; Global mRNA translation impairment has been described during the course of apoptosis in both mammalian and yeast. Nevertheless, the molecular pathways modulating translation during different scenarios of yeast apoptosis are still largely unexplored. Here we show by polysome profile analysis an impairment in capdependent translation initiation, correlated with alterat...
Geographic variation in sardine population traits: implications for stock asses...
Silva, Maria Alexandra Cordeiro de Almeida eTese dout., Ciências e Tecnologias das Pescas, Universidade do Algarve, 2007 ; This study integrates information on geographical and temporal variability of body morphometry, maturity-at-length, growth and population dynamics, to describe population structure of sardine within the Atlanto-Iberian stock region and adjacent waters and assist the de nition of stock units. Biological information was collected regu...
O património cultural do concelho de Sátão : prolegómenos para a sua musealização
Silva, Maria Alexandra Taveira Marques daDissertação de mestrado em Museologia e Património Cultural apresentada à FLUC
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