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Mitochondrial complex I dysfunction induced by cocaine and cocaine plus morphin...

Mitochondrial function and energy metabolism are affected in brains of human cocaine abusers. Cocaine is known to induce mitochondrial dysfunction in cardiac and hepatic tissues, but its effects on brain bioenergetics are less documented. Furthermore, the combination of cocaine and opioids (speedball) was also shown to induce mitochondrial dysfunction. In this work, we compared the effects of cocaine and/or mor...

As visitas pastorais na diocese do Porto : (1675-1800) : os comportamentos desv...