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Aminodi(hetero)arylamines in the thieno[3,2-b]pyridine series : synthesis, effe...
Callhelha, Ricardo C.; Ferreira, Isabel C. F. R.; Peixoto, Daniela; Abreu, Rui M. V.; Silva, L. A. Vale; Pinto, Eugénia; Lima, Raquel T.Three aminodi(hetero)arylamines were prepared via a palladium-catalyzed C-N Buchwald-Hartwig coupling of methyl 3-aminothieno[3,2-b]pyridine-2-carboxylate with different bromonitrobenzenes, followed by reduction of the nitro groups of the coupling products to the corresponding amino compounds. The aminodi(hetero)arylamines thus obtained were evaluated for their growth inhibitory effect on four human tumor cell ...
Data: 2012
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Origem: RepositóriUM - Universidade do Minho
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