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Dois casos de Quérion por Trichophyton mentagrophytes
Silva, I.V.; Morais, R.B.; Francisco, T.; Dessai, S.; Pastilha, P.; Cunha, F.RESUMO Introdução: O Quérion é uma forma rara e inflamatória de tinea capitis causada por fungos dermatófitos. O diagnóstico é dificultado pela demora no exame cultural e possibilidade de várias etiologias no diagnóstico diferencial. O tratamento é prolongado e implica o recurso a antifúngicos sistémicos. Novos fármacos têm sido considerados após a descontinuação da griseofulvina em Portugal. Casos clínicos: Ap...
Endogenous angiotensin II modulates nNOS expression in renovascular hypertension
Pereira,T.M.C.; Balarini,C.M.; Silva,I.V.; Cabral,A.M.; Vasquez,E.C.; Meyrelles,S.S.Nitric oxide (NO) influences renal blood flow mainly as a result of neuronal nitric oxide synthase (nNOS). Nevertheless, it is unclear how nNOS expression is modulated by endogenous angiotensin II, an inhibitor of NO function. We tested the hypothesis that the angiotensin II AT1 receptor and oxidative stress mediated by NADPH oxidase contribute to the modulation of renal nNOS expression in two-kidney, one-clip ...
ClC-5 chloride channel and kidney stones: what is the link?
Silva,I.V.; Morales,M.M.; Lopes,A.G.Nephrolithiasis is one of the most common diseases in the Western world. The disease manifests itself with intensive pain, sporadic infections, and, sometimes, renal failure. The symptoms are due to the appearance of urinary stones (calculi) which are formed mainly by calcium salts. These calcium salts precipitate in the renal papillae and/or within the collecting ducts. Inherited forms of nephrolithiasis relat...
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