Mestrado, Educação Pré-Escolar e Ensino do 1º Ciclo do Ensino Básico, 3 de Julho de 2013, Universidade dos Açores (Relatório de Estágio). ; O presente relatório de estágio teve como objetivo primordial aprofundar e compreender as estratégias de intervenção pedagógica na aquisição da leitura e da escrita, no sentido de progressivamente construir uma prática pedagógica de qualidade, que respeite as necessidades ...
Tese de doutoramento, Ciências Biomédicas (Neurociências), Universidade de Lisboa, Faculdade de Medicina, 2012 ; Nowadays, life expectancy has increased and gradually the prevalence of neurodegenerative disorders in the aging population began to represent a major public health problem. Alzheimer’s disease (AD) is the most common dementia and affects millions of older adults. Despite recent advances in the know...
Dextrin, a glucose polymer with low molecular weight, was used to develop a fully resorbable hydrogel, without using chemical initiators. Dextrin was first oxidized (oDex) with sodium periodate and then cross-linked with adipic acid dihidrazide, a nontoxic cross-linking molecule. Furthermore, a new bidimensional composite hydrogel, made of oxidized dextrin incorporating dextrin nanogels (oDex-nanogel), was also...
Background: Mild cognitive impairment (MCI) is considered to be an early stage of a neurodegenerative disorder, particularly Alzheimer’s disease, and the clinical diagnosis requires the objective demonstration of cognitive deficits. The aim of the present study was to evaluate the predictive value of MCI for the conversion to dementia when using four different verbal memory tests (Logical Memory, LM; California...
Diagnosis of mild cognitive impairment relies on the presence of memory complaints. However, memory complaints are very frequent in healthy people. The objective of this study was to determine the severity and type of memory difficulties presented by elderly patients who seek for clinical help, as compared to the memory difficulties reported by subjects in the community. Assessment of subjective memory complain...
Dissertação de mestrado em Optometria Avançada ; As condições ambientais, nomeadamente radiação infravermelha, ultravioleta e humidade relativa, tanto em ambiente exterior como em ambiente interior, têm uma importância significativa no conforto e bem-estar ocular. Alterações nessas condições, podem levar a desconforto ocular, que se reflete no aparecimento ou aumento de sinais e/ou sintomas oculares. Estes, po...
Background: Dementia and cognitive impairment associated with aging are a major medical and social concern. Neuropsychological testing is a key element in the diagnostic procedures of Mild Cognitive Impairment (MCI), but has presently a limited value in the prediction of progression to dementia. We advance the hypothesis that newer statistical classification methods derived from data mining and machine learning...
Dissertação lic., Ciências Biomédicas, Departamento de Ciências Biomédicas e Medicina da Universidade do Algarve, 2011 ; O vanádio foi descoberto em 1802, e hoje é estudado devido aos seus efeitos biológicos e fisiológicos. Por este motivo, tem sido aplicado em vários estudos bioquÃmicos, biológicos, toxicológicos e terapêuticos, revelando inúmeras propriedades biomédicas e efeitos terapêutic...
Este resumo faz parte de: Book of abstracts of the Meeting of the Institute for Biotechnology and Bioengineering, 2, Braga, Portugal, 2010. A versão completa do livro de atas está disponível em: http://hdl.handle.net/1822/10968
Dissertação de mestrado em Biotecnologia e Bio-Empreendedorismo em Plantas Aromáticas e Medicinais ; Type 2 DM is a metabolic disorder that results from genetic and environmental factors and affects 100 million people worldwide. It is characterized by hyperglycemia due to: i) decreased secretion of insulin by the pancreas and ii) resistance to the action of insulin in tissues as muscle, liver and adipocytes, l...
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