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Towards bioinspired superhydrophobic poly(L-lactic acid) surfaces using phase i...
Shi, Jun; Alves, N. M.; Mano, J. F.The water repellency and self-cleaning ability of many biological surfaces has inspired many fundamental and practical studies related to the development of synthetic superhydrophobic surfaces. However, the investigation of such substrates made of biodegradable polymers has been scarce. Simple approaches based on a single step, performed at room temperature (and pressure), were implemented to obtain superhydrop...
Chitosan coated alginate beads containing poly(N-isopropylacrylamide) for dual-...
Shi, Jun; Alves, N. M.; Mano, J. F.Chitosan coated alginate beads containing poly(N-isopropylacrylamide) (PNIPAAM), were prepared to be used as a controlled pH/temperature sensitive drug delivery system with improved encapsulation efficiency and delayed release rate. The studied beads were characterized by differential scanning calorimetry, scanning electron microscopy, and Fourier transform infrared spectroscopy. Water uptake and release studie...
Drug release of pH/temperature-responsive calcium alginate/poly(N-isopropylacry...
Shi, Jun; Alves, N. M.; Mano, J. F.A series of semi-interpenetrating, polymer network (semi-IPN), hydrogel beads, composed of calcium alginate (Ca-alginate) and poly(N-isopropylacrylamide) (PNIPAAM), were prepared for a pH/temperature-sensitive drug delivery study. The equilibrium swelling showed the independent pH- and thermo- responsive nature of the developed materials. At pH¼2.1, the release amount of indomethacin incorporated into these bea...
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