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Salmonella Enteritidis bacteriophage candidates for phage therapy of poultry
Sillankorva, Sanna; Pleteneva, E. A.; Shaburova, O. V.; Santos, Sílvio; Carvalho, Carla A. O. C. M.; Azeredo, Joana; Krylov, V. N.Aims: Salmonella is a worldwide foodborne pathogen causing acute enteric infections in humans. In the recent years, the use of bacteriophages has been suggested as a possible tool to combat this zoonotic pathogen in poultry farms. This work aims to isolate and perform comparative studies of a group of phages active against a collection of specific Salmonella Enteritidis strains from Portugal and England. Also...
Selection and characterization of a multivalent Salmonella phage and its produc...
Santos, Sílvio; Fernandes, E.; Carvalho, Carla M.; Sillankorva, Sanna; Krylov, V. N.; Pleteneva, E. A.; Shaburova, O. V.; Nicolau, Ana; Ferreira, E. C.We report the selection and amplification of the broad-host-range Salmonella phage phi PVP-SE1 in an alternative nonpathogenic host. The lytic spectrum and the phage DNA restriction profile were not modified upon replication in Escherichia coli Bl21, suggesting the possibility of producing this phage in a nonpathogenic host, contributing to the safety and easier approval of a product based on this Salmonella bi...
Production of a salmonella bacteriophage in a non-pathogenic E. coli strain
Santos, Sílvio; Fernandes, E.; Krylov, V. N.; Pleteneva, E. A.; Shaburova, O. V.; Nicolau, Ana; Ferreira, E. C.; Azeredo, Joana
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