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Response of high-risk of recurrence/progression bladder tumours expressing sial...

Lima, Luís; Severino, Paulo; Silva, Mariana; Miranda, Andreia; Tavares, Ana; Pereira, Sofia; Fernandes, Elisabete; Cruz, Ricardo; Amaro, Teresina

High risk of recurrence/progression bladder tumours is treated with Bacillus Calmette-Guérin (BCG) immunotherapy after complete resection of the tumour. Approximately 75% of these tumours express the uncommon carbohydrate antigen sialyl-Tn (Tn), a surrogate biomarker of tumour aggressiveness. Such changes in the glycosylation of cell-surface proteins influence tumour microenvironment and immune responses that m...


Overexpression of tumour-associated carbohydrate antigen sialyl-Tn in advanced ...

Ferreira, José Alexandre; Videira, Paula; Lima, Luís; Pereira, Sofia; Silva, Mariana; Carrascal, Milene; Severino, Paulo; Fernandes, Elisabete

Little is known on the expression of the tumour-associated carbohydrate antigen sialyl-Tn (STn), in bladder cancer. We report here that 75% of the high-grade bladder tumours, presenting elevated proliferation rates and high risk of recurrence/progression expressed STn. However, it was mainly found in non-proliferative areas of the tumour, namely in cells invading the basal and muscle layers. STn was also found ...


MARRT Pipeline:pipeline for markerless augmented reality systems based on real-...

Severino Paulo Gomes Neto

Nowadays, with the increase of computational power and the studies on usability, real-time systems and photo-realism, the requirements of any computer system are more complex and sophisticated. Augmented Reality systems are not an exception in their attempt for solving users‟ real life problems with reduced risk, time expending or learning complexity. Such systems may be classified as marker-based or mark...

Data: 2009   |   Origem: OASIS br

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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia