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Surface charaterization of soft contact lenses by atomic force microscopy
Lira, Madalena; Costa, Manuel F. M.; Vazquez-Dorrio, José B.; Serra, Carmen; Oliveira, M. Elisabete; Franco, SandraThe aim of this study is to analyze surface properties of different hydrogel and silicone-hydrogel contact lenses (CL) using Atomic Force Microscopy (AFM) Several commercial CL prepared by the same method of manufacture (cast-moulding), with different monomers composition, water content and surface treatment were used in this study. Surface roughness analysis was performed using AFM on Tapping® Mode using st...
Surface phosphorylation of chitosan significantly improves osteoblast cell viab...
López Pérez, Paula M.; Silva, Ricardo M. P. da; Serra, Carmen; Pashkuleva, I.; Reis, R. L.Chitosan biocompatibility is often associated with the structural similarities with glycosaminoglycans (GAGs). Although all of the GAGs are built from repeating disaccharide units and some of them contain N-glucosamine (the main hexosamine in the chitosan backbone), all of them also contain negatively charged functional groups. These charged units are believed to have a crucial role for the formation of proteog...
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