Encontrados 15 documentos, a visualizar página 1 de 2
Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an ...
Sereno, José; Rodrigues-Santos, Paulo; Vala, HelenaCyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, regardless of nephrotoxicity, which depends on the duration of drug exposure. The mechanisms and biomarkers underlying the transition from CsA-induced renal dysfunction to nephrotoxicity deserve better elucidation, and would help clinical decisions. This study aimed to clarify these issues, using a rat model of s...
Inhibition of Bladder Tumor Growth by Chitooligosaccharides in an Experimental ...
Fernandes, João C.; Sereno, José; Garrido, Patricia; Parada, Belmiro; Cunha, Maria F. X.; Reis, Flávio; Pintado, M. E.; Santos-Silva, AliceUrinary bladder cancer is one of the most common cancers worldwide, with the highest incidence in industrialized countries. Patients with cancer commonly use unconventional and complementary therapy including nutraceuticals. In this study we evaluated the efficacy of chitooligosaccharides (in orange juice) in rat bladder cancer chemoprevention and as therapeutic agent, on a rat model of urinary bladder carcinog...
Nascimento de bezerros normais após inseminação artificial utilizando espermato...
Costa,Priscila de Melo; Martins,Carlos Frederico; Franco,Vanessa de Oliveira; Rezende,Luiz Osvaldo Fonseca; Sereno,José Robson BezerraO objetivo deste estudo foi avaliar as características morfológicas e funcionais dos espermatozóides bovinos recuperados de epidídimos resfriados por longos períodos e posteriormente criopreservados. Testículos bovinos foram coletados no abatedouro, transportados ao laboratório e armazenados a 5°C por 0, 24, 48 e 72 horas (n=10 para cada tratamento). Os espermatozóides foram extraídos de cada epidídimo, ava...
Weight and age at puberty and their correlations with morphometric measurements...
Ferra, Janine de Campos; Cieslak, Silvia; Sartori Filho, Roberto; Pimentel, Concepta Margaret McManus; Martins, Carlos FredericoABSTRACT: The objective of this study was to identify and to correlate parameters that characterize puberty and estimate the age and weight of Suffolk ewe lambs in Mato Grosso do Sul. This study was carried out with twenty-two Suffolk ewe lambs for 256 days. Blood samples were collected from the jugular vein and centrifugated and the plasma were stored at -20°C until analysis of progesterone (P4) concentration ...
Weight and age at puberty and their correlations with morphometric measurements...
Ferra,Janine de Campos; Cieslak,Silvia; Sartori Filho,Roberto; McManus,Connie; Martins,Carlos Frederico; Sereno,José Robson BezerraThe objective of this study was to identify and to correlate parameters that characterize puberty and estimate the age and weight of Suffolk ewe lambs in Mato Grosso do Sul. This study was carried out with twenty-two Suffolk ewe lambs for 256 days. Blood samples were collected from the jugular vein and centrifugated and the plasma were stored at -20°C until analysis of progesterone (P4) concentration by radioim...
Eficácia do celecoxibe versus aspirina na prevenção/regressão do carcinoma da B...
Sereno, José Vitor OliveiraO carcinoma da bexiga é uma patologia com taxas de incidência e prevalência e valores de morbilidade e mortalidade que continuam a preocupar a comunidade médica e científica. Dados estatísticos revelam que a taxa de mortalidade tem vindo a diminuir nas últimas década devido aos avanços médico-cirúrgicos,enquanto a taxa de incidência continua a aumentar. É devido a estes factos que cada vez mais se procura perce...
Erythropoietin promotes deleterious cardiovascular effects and mortality risk i...
Piloto, Nuno; Teixeira, Helena M.; Teixeira-Lemos, Edite; Parada, Belmiro; Garrido, Patrícia; Sereno, José; Pinto, Rui; Carvalho, Lina; Costa, ElísioAthletes who abuse recombinant human erythropoietin (rhEPO) consider only the benefit to performance and usually ignore the potential short and long-term liabilities. Elevated haematocrit and dehydratation associated with intense exercise may reveal undetected cardiovascular risk, but the mechanisms underlying it remain to be fully explained. This study aimed to evaluate the cardiovascular effects of rhEPO in r...
Genetic diversity of Brazilian Pantaneiro horse and relationships among horse b...
Sereno,Fabiana Tavares Pires de Souza; Sereno,José Robson Bezerra; Vega-Pla,Jose Luis; Kelly,Lucy; Bermejo,Juan Vicente DelgadoThe objective of this work was to evaluate the genetic diversity of Brazilian Pantaneiro horse by microsatellite markers, investigate the effect of genetic bottlenecks and estimate genetic differentiation among four horse breeds. Genetic variation was estimated through allele frequencies and mean breed heterozygosity. Nei's genetic distances among the breeds Pantaneiro, Thoroughbred, Arabian, Spanish Pure Breed...
DNA testing for parentage verification in a conservation nucleus of Pantaneiro ...
Sereno,Fabiana Tavares Pires de Souza; Sereno,José Robson Bezerra; Vega-Pla,Jose Luis; Delgado,Juan VicenteWe investigated the genealogy of the in situ conservation nucleus of the Pantaneiro horse using DNA microsatellites by evaluating 101 horses, the group consisting of 71 adult horses (3 stallions, 40 male and 31 mares) and 27 foals (14 colts and 13 fillies). Genomic DNA was extracted from hair roots and genotyped using 12 microsatellite markers (AHT4, AHT5, ASB2, ASB17, ASB23, HMS3 HMS6, HMS7, HTG4, HTG10, LEX33...
Cytogenetic and molecular analysis of the Pantaneiro cattle breed
Issa,Érica Cunha; Jorge,Wilham; Sereno,José Robson BezerraThe objective of this work was to characterize Pantaneiro cattle genetically through its paternal ancestry by the morphology of the Y chromosome, whether submetacentric or acrocentric, as well as to identify the maternal ancestry through mitochondrial DNA. The karyotype and mitochondrial DNA of 12 bulls of Pantaneiro breed were analyzed. The Y chromosome was analyzed in lymphocyte metaphases and the mitochondri...
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