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Prognostic Value of VEGF in Patients Submitted to Percutaneous Coronary Interve...
Ramos, C; Napoleão, P; Selas, M; Freixo, C; Viegas Crespo, AM; Mota Carmo, M; Cruz Ferreira, R; Pinheiro, TWe examined the longitudinal changes of VEGF levels after percutaneous coronary intervention for predicting major adverse cardiac events (MACE) in coronary artery disease (CAD) patients. VEGF was measured in 94 CAD patients' serum before revascularization, 1-month and 1-year after. Independently of clinical presentation, patients had lower VEGF concentration than a cohort of healthy subjects (median, IQ: 15.9, ...
Serial Changes in Oxidized Low-Density Lipoprotein Associated with Culprit Vess...
Napoleão, P; Selas, M; Toste, A; Turkman, A; Andreozzi, V; Viegas-Crespo, AM; Pinheiro, T; Cruz Ferreira, RThe aim of the present study was to investigate variations in oxidized LDL (oxLDL) at the onset of acute myocardial infarction (AMI) and over the recovery period, exploring their relationship with coronary disease severity. A follow-up of 50 AMI patients was evaluated against 25 healthy volunteers (reference group). The AMI patients were evaluated at three time points: at admission before the administration of ...
Variações de Marcadores Inflamatórios no Enfarte Agudo do Miocárdio: um Estudo ...
Napoleão, P; Santos, MC; Selas, M; Viegas-Crespo, AM; Pinheiro, T; Cruz Ferreira, RActualmente a inflamação é considerada uma componente importante na aterosclerose, desde o seu início até à ruptura da placa seguida de trombose e da progressiva obstrução do vaso. A ruptura da cápsula fibrótica da placa expõe factores de tecido presentes no seu núcleo necrótico que induzem o processo inflamatório, promovendo a adesão celular e a coagulação e que conduzem à formação do trombo. Por seu turno, vá...
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