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Chronic stress disrupts neural coherence between cortico-limbic structures

Dias, Nuno S.; Oliveira, João Filipe; Correia, Mariana; Gama-Pereira, Filipa; Sardinha, Vanessa Morais; Lima, Ana; Oliveira, Ana Filipa

Chronic stress impairs cognitive function, namely on tasks that rely on the integrity of cortico-limbic networks. To unravel the functional impact of progressive stress in cortico-limbic networks we measured neural activity and spectral coherences between the ventral hippocampus (vHIP) and the medial prefrontal cortex (mPFC) in rats subjected to short term stress (STS) and chronic unpredictable stress (CUS). CU...

Data: 2013   |   Origem: CiencIPCA

Chronic stress disrupts neural coherence between cortico-limbic structures

Oliveira, João F.; Dias, N. S.; Correia, Mariana; Pereira, Filipa Gama; Sardinha, Vanessa Morais; Lima, Ana Raquel; Oliveira, Ana Filipa Martins

The authors would like to thank Rui Gomes for the help in the application of electrophysio- logical techniques and Luís Martins and Miguel Carneiro for the histological preparations. ; Chronic stress impairs cognitive function, namely on tasks that rely on the integrity of cortico-limbic networks. To unravel the functional impact of progressive stress in cortico-limbic networks we measured neural activity and ...


Gelatin microparticles aggregates as three-dimensional scaffolding system in ca...

García Cruz, D. M.; Sardinha, Vanessa Morais; Escobar Ivirico, J. L.; Mano, J. F.; Gómez Ribelles, J. L.

A three-dimensional (3D) scaffolding system for chondrocytes culture has been produced by agglomeration of cells and gelatin microparticles with a mild centrifuging process. The diameter of the microparticles, around 10 μ, was selected to be in the order of magnitude of the chondrocytes. No gel was used to stabilize the construct that maintained consistency just because of cell and extracellular matrix (ECM) ad...


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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia