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Optical coherence tomography: automatic retina classification through support v...
Bernardes, Rui; Serranho, Pedro; Santos, Torcato; Gonçalves, Valter; Cunha-Vaz, JoséOptical coherence tomography (OCT) is becoming one of the most important imaging modalities in ophthalmology due to its non-invasiveness and by allowing the visualisation the human retina structure in detail. It was recently proposed that OCT data embeds functional information from the human retina. Specifically, it was proposed that blood–retinal barrier status information is present within OCT data from the h...
Synthtic OCT Data for image processing performance testing
Serranho, Pedro; Maduro, Cristina; Santos, Torcato; Vaz, José Cunha; Bernardes, RuiThe use of synthetic images is needed for testing the performance of image processing methods in order to establish a ground truth to test performance metrics. However, these synthetic images do not represent real applications. The aim of this paper is to build a mathematical model to obtain a synthetic noise-free image mimicking a real Optical Coherence Tomography (OCT) B-scan or volume from the human retina, ...
Ocular fundus Imaging: from structure to function
Serranho, Pedro; Maduro, Cristina; Santos, Torcato; Bernardes, Rui; Vaz, José Cunha; Araújo, Adérito; Barbeiro, SílviaImaging the ocular fundus, namely the retina, to detect and/or monitor changes over time from the healthy condition is of fundamental importance to assess onset and disease progression and is a valuable tool to understand the basic mechanisms of ocular diseases. Current trends point to the need for less or non-invasive approaches, to the need for detailed (higher spatial and temporal resolution) imaging systems...
Noninvasive evaluation of retinal leakage using optical coherence tomography
Bernardes, Rui; Santos, Torcato; Serranho, Pedro; Lobo, Conceição; Cunha-Vaz, JoséPurpose: To demonstrate the association between changes in the blood-retinal barrier (BRB) identified by fluorescein leakage and those in the optical properties of the human retina determined by optical coherence tomography (OCT) and show how these changes can be quantified and their location identified within the retina. Methods: Two imaging techniques were applied: the retinal leakage analyzer, to map BRB fun...
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