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Value of patch tests in clindamycin-related drug eruptions

Pereira, N; Canelas, MM; Santiago, F; Brites, MM; Gonçalo, Margarida

Background. Patch tests help to confirm the aetiology of the cutaneous adverse drug reactions involving delayed hypersensitivity mechanisms, but the results vary with the pattern of skin reaction and the culprit drug. Objectives. To analyse the results of patch tests in patients with cutaneous adverse drug reactions imputable to clindamycin and assess their contribution to the diagnosis. Patients and methods. B...


Case for diagnosis

Santiago, F; Reis, JP

This report describes a patient with clinical and histopathological findings compatible with angiolymphoid hyperplasia with eosinophilia. This benign vascular hyperplasia should be recognized and differentiated from Kimura's disease.


Adverse cutaneous reactions to epidermal growth factor receptor inhibitors: a s...

Santiago, F; Gonçalo, Margarida; Reis, JP; Figueiredo, A

BACKGROUND: Cetuximab and erlotinib, epidermal growth factor receptor inhibitors, often cause peculiar adverse cutaneous reactions. OBJECTIVES: Our aim was to evaluate adverse cutaneous reactions and their management in patients undergoing treatment with cetuximab and erlotinib. PATIENTS AND METHODS: Between March/2005 and September/2009, we observed 14 patients with a mean age of 59.6 years undergoing treatm...


Linear psoriasis - a case report.

Brinca, A; Santiago, F; Serra, D; Andrade, P; Vieira, R; Figueiredo, A

A 56-year-old woman presented with a 3-month history of erythematous plaques covered by scales and limited to the right side of her body. The plaques were arranged along Blaschko's lines with a marked mid-line cutoff. The histopathologic analysis of a skin biopsy in conjunction with the anamnesis allowed the diagnosis of linear psoriasis. Our patient showed a good clinical response to antipsoriatic treatment.


Multiple glomus tumors and segmental neurofibromatosis: there are no coincidences

Cabral, R; Santiago, F; Tellechea, O

Segmental neurofibromatosis is a rare subtype of neurofibromatosis type 1 (NF1). Glomus tumors are uncommon benign tumors. The authors report the association between these two rare conditions, not yet reported.


Allergic contact dermatitis to shoes induced by dimethylfumarate: A new allerge...

Santiago, F; Andrade, P; Gonçalo, Margarida; Mascarenhas, R; Figueiredo, A

BACKGROUND: In the last two years several cases of severe contact dermatitis related to newly acquired sofas and armchairs originating from China have been published. The responsible allergen is dimethylfumarate (DMF), an extremely potent sensitizer and irritant found in sachets inside the furniture. Recently, cases of contact dermatitis related to shoes and riding helmets have also been described. METHODS: We...


Epicutaneous patch testing in drug hypersensitivity syndrome (DRESS)

Santiago, F; Gonçalo, Margarida; Vieira, R; Coelho, S; Figueiredo, A

BACKGROUND: In some patterns of cutaneous adverse drug reactions, and depending on the culprit drug, patch testing has been helpful in confirming its cause. Its value in Drug Rash with Eosinophilia and Systemic Symptoms (DRESS) has not been established in a large cohort of patients. OBJECTIVE: The aim of the present study is to evaluate the safety and usefulness of patch testing in DRESS. PATIENTS/METHODS: Betw...


Algodão em consórcios agroecológicos.

VALE, D. G.; BLOCH, D.; ALBUQUERQUE, F. A. de; SANTIAGO, F. S.; GUIMARAES, F. M.; ALVES, I.; SILVA, J. C. A. da; ARRIEL, N. H. C.

2009

Data: 2009   |   Origem: OASIS br

A remarkable case of cutaneous metastatic breast carcinoma

Santiago, F; Saleiro, S; Brites, MM; Frutuoso, C; Figueiredo, A

We describe a 50-year-old woman with a 5-month history of multiple asymptomatic papulonodular lesions on the left chest area. Biopsy was consistent with cutaneous metastases from a ductal breast carcinoma. No distant metastatic lesions were detected. The patient was referred to the Gynecologic Oncology Department. Treatment included chemotherapy, radiotherapy and surgery. At present the patient is well with no ...


Unilateral progressive osseous heteroplasia

Santiago, F; Veira, R; Cordeiro, M; Tellechea, O; Figueiredo, A

A 50-year-old male patient presented with firm subcutaneous nodules and plaques with a gritty texture, unilaterally affecting the left side of the trunk and the left limbs. These lesions had had a progressive course since early childhood and caused functional impairment. There was no family history of similar disorders. No phospho-calcium metabolism abnormalities were observed. Biopsies of the affected areas de...


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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia