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Hyperosmotic stress induces metacaspase - and mitochondria - dependent apoptosi...
Silva, Rui D.; Sotoca, Roberto; Johansson, Björn; Ludovico, Paula; Sansonetty, Filipe; Silva, Manuel T.; Peinado, José M.; Côrte-Real, ManuelaProva tipográfica (In Press) ; During the last years, several reports described an apoptosis-like programmed cell death process in yeast in response to different environmental aggressions. Here, evidence is presented that hyperosmotic stress induces in Saccharomyces cerevisiae a cell death process accompanied by morphological and biochemical indicators of apoptotic programmed cell death, namely chromatin conde...
Acetic acid induces a programmed cell death process in the food spoilage yeast ...
Ludovico, Paula; Sansonetty, Filipe; Silva, Manuel T.; Côrte-Real, ManuelaHere we show that 320-800 mM acetic acid induces in Zygosaccharomyces bailii a programmed cell death (PCD) process that is inhibited by cycloheximide, is accompanied by structural and biochemical alterations typical of apoptosis, and occurs in cells with preserved mitochondrial and plasma membrane integrity (as revealed by rhodamine 123 (Rh123) and propidium iodide (PI) staining, respectively). Mitochondrial ul...
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