Encontrados 19 documentos, a visualizar página 1 de 2
Cutaneous manifestations of antiphospholipid syndrome: a review of the clinical...
Pinto-Almeida, T.; Caetano, M.; Sanches, M.; Selores, M.Antiphospholipid syndrome is a relatively recent systemic autoimmune disorder defined by thrombotic events and/or obstetric complications in the presence of persistent elevated antiphospholipid antibodies. It is characterized by a wide spectrum of clinical presentations and virtually any organ system or tissue may be affected by the consequences of vascular occlusion. Diagnosis is sometimes difficult and althou...
Vulvoperineal Crohn's disease responsive to metronidazole
Rosmaninho, A.; Sanches, M.; Salgado, M.; Alves, R.; Selores, M.Crohn's disease is a multisystem chronic granulomatous inflammatory disease that primarily affects the gastrointestinal tract. In the majority of the cases, the cutaneous manifestations follow the intestinal disease, but occasionally dermatological lesions are the inaugural event and may constitute the only sign of the disease. Vulvoperineal involvement is rare, may precede bowel symptoms by months to years and...
Photoallergic reaction to cyamemazine.
Fernandes, I.; Vilaça, S.; Lobo, I.; Sanches, M.; Costa, V.; Selores, M.A 50-year-old man presented with a scaly erythema of the face, upper chest, forearms, and dorsum of the hands. He has been treated with cyamemazine for 6 months. Photopatch tests were performed and the patient was diagnosed with photoallergic reaction to cyamemazine. The drug was discontinued and a course of oral steroids was prescribed. The patient was advised to avoid light exposure. There has been no evidenc...
Case for diagnosis
Fernandes, I.; Sanches, M.; Alves, R.; Selores, M.Abstract We report a clinical case of a rare variant of pemphigus - pemphigus herpetiformis - which combines the clinical features of dermatitis herpetiformis with the immunological findings of pemphigus. Due to its atypical presentation, it is frequently misdiagnosed as dermatitis herpetiformis. It is basically characterized by the herpetiform pattern of skin lesions, severe pruritus and by the presence of eos...
Caso dermatológico: Síndrome de Gianotti-Crosti
Oliveira, A.; Sanches, M.; Selores, M.ABSTRACT Gianotti-Crosti syndrome (GCS) is a disease characterized by a symmetrical erythematopapulous, acral-based eruption. It affects mainly children under four years of age. In most cases a relationship with a viral infection or a vaccine can be established. The course of GCS is benign and self-limited, the manifestations disappearing within two to eight weeks, with no recurrence. We report the case of a fi...
Rituximab no tratamento de pênfigo vulgar refractário
Fernandes, I.; Sanches, M.; Velho, G.; Selores, M.O pênfigo vulgar é uma doença bolhosa auto-imune rara, que atinge a pele e as mucosas. Geralmente tem um curso clínico severo, sendo necessário o recurso a terapêutica prolongada com corticóides sistémicos e outros fármacos imunossupressores, que podem conduzir a efeitos adversos graves. O rituximab é um anticorpo monoclo- nal quimérico dirigido ao antigénio CD20, expresso pelos linfócitos B. Recentemente, têm ...
Pellagra as the initial presentation of Crohn disease
Rosmaninho, A.; Sanches, M.; Fernandes, I.; Pinto-Almeida, T.; Vilaça, S.; Oliveira, A.; Selores, M.Pellagra is a nutritional disease caused by the deficiency of niacin. We describe a case of pellagra as the initial presentation of Crohn disease, which has been rarely described in the literature.
Vesico-bullous subacute cutaneous lupus erythematosus – An uncommon entity succ...
Pinto-Almeida, T.; Sanches, M.; Alves, R.; Selores, M.Vesico-bullous subacute cutaneous lupus erythematosus is an uncommon and severe presentation. The authors report an exuberant case of vesico-bullous subacute cutaneous lupus erythematosus successfully treated with dapsone and hydroxychloroquine
Foscarnet-induced penile ulceration
Torres, T.; Fernandes, I.; Sanches, M.; Selores, M.Foscarnet is used to treat infections with herpes viruses, including drug-resistant cytomegalovirus (CMV) and infections with herpes viruses 1 and 2 (HSV-1 and HSV-2). There are some reports of intravenous foscarnet-induced penile and vulvar ulceration. The authors report a case of severe penile ulcers after the initiation of intravenous foscarnet therapy
Penile Kaposi sarcoma: A case of complete resolution with highly active antiret...
Pinto-Almeida, T.; Torres, T.; Rosmaninho, A.; Sanches, M.; Alves, R.; Caetano, M.; Selores, M.Kaposi sarcoma remains an important cause of morbidity in HIV-infected patients. Regardless of the recent pharmacological progress, treatment of this malignancy is still disappointing. We report the case of a patient with Kaposi sarcoma in an unusual localization, the penis, which completely resolved with highly active antiretroviral therapy alone
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